Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1994-04-26
1995-04-25
Lee, Lester L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 14, 514 12, 514 21, 530324, 530325, 530326, 530327, A61K 3700, A61K 3702, C07K 500, C07K 700
Patent
active
054098980
ABSTRACT:
The invention is directed to compositions and methods for treating an infection caused by an organism susceptible to a .beta.-lactam antibiotic comprising two or more active agents. In one embodiment, the composition comprises: (1) a .beta.-lactam antibiotic and (2) a cationic oligopeptide. In another embodiment, the invention is also directed to a composition comprising: (1) a .beta.-lactam antibiotic which inhibits the growth of Enterobacteriaceae bacteria and (2) at least one membrane active substance. Further, the invention is also directed to improved methods for screening potential bactericidal compositions in vitro wherein components of an active complement cascade are included.
REFERENCES:
patent: 4107298 (1978-08-01), Luning
patent: 4543252 (1985-09-01), Lehrer et al.
patent: 4659692 (1987-04-01), Lehrer et al.
patent: 4810777 (1989-03-01), Zasloff
patent: 5045531 (1991-09-01), Berkowitz
Zasloff, P.N.A.S., vol. 84, 1987, pp. 5449-5453.
Zasloff et al., P.N.A.S., vol. 85, 1988 pp. 910-913.
Christensen et al., P.N.A.S., vol. 85, 1988, pp. 5072-5076.
Blake James J.
Cosand Wesley J.
Darveau Richard C.
Bristol--Myers Squibb Company
Davenport A. M.
Lee Lester L.
Poor Brian W.
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