Compositions and methods for treating hyperimmune response...

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Binds hormone or other secreted growth regulatory factor,...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C424S141100, C424S142100, C424S134100, C424S130100, C424S078040, C514S912000

Reexamination Certificate

active

10372644

ABSTRACT:
The present invention comprises and utilizes methods and compositions for treating hyperimmune reactions in the eye. Compositions comprising antibodies to gamma interferon alone and in combination with other drugs are described. Also disclosed in the invention are methods of applying a composition comprising interferon gamma antibodies topically to the eye to treat hyperimmune reactions, such as transplant rejection, autoimmune diseases of the eye, and ocular disorders incidental to or connected with autoimmune diseases.

REFERENCES:
patent: 4704362 (1987-11-01), Itakura et al.
patent: 5597567 (1997-01-01), Whitcup et al.
patent: 5888511 (1999-03-01), Skurkovich et al.
patent: 6180370 (2001-01-01), Queen et al.
patent: 6534059 (2003-03-01), Skurkovich et al.
patent: 6861056 (2005-03-01), Skurkovich et al.
patent: WO 87/02670 (1987-05-01), None
Skurkovich et al. Am. J. Opthalm. 133: 829-830, Jun. 2002.
Novick et al. The EMBO J. 2: 1527-1530, 1983.
Singh et al. Indian J. Med. Res. 107: 53-67, 1998, abstract.
Beychok, Cells of Immunoglobulin Synthesis, Academic Press, New York, 1979.
Bird et al., 1988, Science 242:423-426.
Feldmann et al. , 1987, In IFN γ, Academic Press, p. 75-89.
Genaro, ed., 1985, Remington's Pharmaceutical Sciences, Mack Publishing Co., Easton, PA.
Gillam and Smith, 1979, Gene, 8, 81-97.
Gringeri et al., 1995, Cell. Mol. Biol. 41(3):381-387.
Gringeri et al., 1996, J. Acquir. Immun. Defic. Syndr., 13:55-67.
Gu et al., 1997, Thrombosis and Hematocyst 77(4):755-759.
Harlow et al., 1989, Antibodies: A Laboratory Manual, Cold Spring Harbor, New York.
Harlow et al., 1999, Using Antibodies: A Laboratory Manual, Cold Spring Harbor Laboratory Press, NY.
Harlow, et al., 1988, In: Antibodies, A Laboratory Manual, Cold Spring Harbor, NY.
Huston et al., 1988, Proc. Natl. Acad. Sci. USA 85:5879-5883.
Queen et al., 1986, Immunol. Rev., 89, 49-68.
Roberts et al., 1987, Nature, 328, 731-734.
Sambrook et al., 1989, Molecular Cloning, A Laboratory Manual, Cold Spring Harbor, NY.
Skurkovich et al., 1974, Nature 217:551-552.
Skurkovich et al., 1975, Annals of Allergy, 35:356-360.
Skurkovich et al., 1992, J. Interferon Res. 12, Suppl. 1:S110.
Skurkovich et al., 1993, Med. Hypoth., 41:177-185.
Skurkovich et al., 1994, Med. Hypoth., 42:27-35.
Tuszynski et al., 1988, Blood, 72:109-115.
Williams et al., eds., 1980, Gray's Anatomy, 36th ed., W.B. Saunders Co., Philadelphia.
Winnacker, 1987, “From Genes to Clones,” VCH Publishers, New York, N.Y.
Wright et al., 1992, Critical Rev. in Immunol. 12(3,4):125-168.
Froyen et al., “Potential therapeutic use of antibodies directed towards HuIFN-γ”,Biotherapy, 10: 49-57 (1997).
Stevens et al., “Synergistic Immunosuppressive Effects Of Monoclonal Antibodies Specific For Interferon-gamma And Tumor Necrosis Factor Alpha”,Transplantation, 50: 856-861 (1990).
Atalla et al., “In Vivo Treatment Of Experimental Uveoretinitis With Monoclonal Antibody To Gamma-Interferon”,Ocular Immunology Today: Proceedings of the 5thInternational Symposium on the Immunology and Immunopathology of the Eye, Tokyo, Mar. 13-15, 1990, pp. 65-68.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Compositions and methods for treating hyperimmune response... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compositions and methods for treating hyperimmune response..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions and methods for treating hyperimmune response... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3820797

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.