Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2007-04-11
2009-12-01
Bowman, Amy (Department: 1635)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C536S023100, C536S024500, C435S320100
Reexamination Certificate
active
07625874
ABSTRACT:
The invention herein provides a mode of treating a disease associated with the regulation of T-Box and N-Myc gene which includes cancers and heart disease in human and other subjects by identifying and administering a compound which modulates T-Box or N-Myc function. The invention also provides polynucleotides, polypeptides, vectors, cells, tissues and organisms useful in the identification and treatment of metabolic syndrome. A number of desirable cell proliferation and senescence regulating aspects are achieved by various embodiments of the present invention.
REFERENCES:
patent: 6506559 (2003-01-01), Fire et al.
Mahato et al., Modulation of gene expression by antisense and antigene oligodeoxynucleotides and small interfering RNA, Jan. 2005, Expert Opinion on Drug Delivery, vol. 2, No. 1, pp. 3-28.
Scherer et al., Approaches for the sequence-specific knockdown of mRNA, 2003, Nat. Biotechnol., 21(12), pp. 1457-1465.
Prince et al., Tbx2 Directly Represses the Expression of the p21 WAF1 Cylclin-Dependent Kinase Inhibitor, 2004, Cancer Research, 64, pp. 1669-1674.
Devroe et al., Retrovirus-delivered siRNA, 2002, BMC Biotechnology, 2:15, pp. 1-5.
Cai Chenleng
Chen Ju
Evans Sylvia
Rosenfeld Michael G
Zhou Wenlai
Bowman Amy
DLA Piper (LLP) US
The Regents of the University of California
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