Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing
Reexamination Certificate
2007-09-04
2007-09-04
Witherspoon, Sikarl A. (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Oxygen containing
C568S329000, C568S330000, C514S680000
Reexamination Certificate
active
11412823
ABSTRACT:
A colchicine derivative and a method of using a colchicine derivative as a pharmacological agent in the treatment of malaria are provided.
REFERENCES:
patent: 3876632 (1975-04-01), Sturm et al.
patent: 4451674 (1984-05-01), Kobayashi et al.
patent: 4467126 (1984-08-01), Zinnen
patent: 4552894 (1985-11-01), Inoue et al.
patent: 4568488 (1986-02-01), Lee-Huang
patent: 4571441 (1986-02-01), Miwa et al.
patent: 4962252 (1990-10-01), Wade
patent: 5316932 (1994-05-01), Bigner et al.
patent: 5328603 (1994-07-01), Velander et al.
patent: 5362857 (1994-11-01), Hock
patent: 5466620 (1995-11-01), Bang
patent: 5470822 (1995-11-01), Younes
patent: 5549840 (1996-08-01), Mondin et al.
patent: 5580898 (1996-12-01), Trojanowski et al.
patent: 5593958 (1997-01-01), Mondin et al.
patent: 5599785 (1997-02-01), Mondin et al.
patent: 5614500 (1997-03-01), Zimmermann
patent: 5661032 (1997-08-01), Miller et al.
patent: 5670691 (1997-09-01), Spangler et al.
patent: 5679530 (1997-10-01), Brentani et al.
patent: 5731281 (1998-03-01), Mondin et al.
patent: 5827679 (1998-10-01), Moore et al.
patent: 5830452 (1998-11-01), Bauer et al.
patent: 5851789 (1998-12-01), Simon et al.
patent: 5886025 (1999-03-01), Pinney
patent: 6000772 (1999-12-01), Miller et al.
patent: 6025331 (2000-02-01), Moses et al.
patent: 6162930 (2000-12-01), Pinney et al.
patent: 6177472 (2001-01-01), Wilson et al.
patent: 6222093 (2001-04-01), Marton et al.
patent: 6232089 (2001-05-01), Buckle et al.
patent: 6258841 (2001-07-01), Uckun et al.
patent: 6306615 (2001-10-01), Beckmann et al.
patent: 6329420 (2001-12-01), Uckun et al.
patent: 6346389 (2002-02-01), Altieri
patent: 6346408 (2002-02-01), Chueh
patent: 6350777 (2002-02-01), Pinney et al.
patent: 6358957 (2002-03-01), Fukumoto et al.
patent: 6372772 (2002-04-01), Kirkpatrick et al.
patent: 6423735 (2002-07-01), Camden et al.
patent: 6423736 (2002-07-01), Camden et al.
patent: 6433187 (2002-08-01), Clark et al.
patent: 6441053 (2002-08-01), Klein et al.
patent: 6451807 (2002-09-01), Emmick et al.
patent: 6458847 (2002-10-01), Wilson et al.
patent: 6462062 (2002-10-01), Camden et al.
patent: 6472541 (2002-10-01), Tsien et al.
patent: 6482043 (2002-11-01), Stout
patent: 6576219 (2003-06-01), Brandt et al.
patent: 6579577 (2003-06-01), Kondo et al.
patent: 6586188 (2003-07-01), Berggren et al.
patent: 6593374 (2003-07-01), Pinney et al.
patent: 6608096 (2003-08-01), Camden et al.
patent: 6620818 (2003-09-01), Davis
patent: 6630492 (2003-10-01), Bauer et al.
patent: 6635434 (2003-10-01), Jakobsen et al.
patent: 6660767 (2003-12-01), Jacobs et al.
patent: 6676944 (2004-01-01), Dalton et al.
patent: 6710065 (2004-03-01), Camden et al.
patent: 6713480 (2004-03-01), Fukumoto et al.
patent: 6720349 (2004-04-01), Quada, Jr. et al.
patent: 6750330 (2004-06-01), Davis et al.
patent: 6846481 (2005-01-01), Gaertig et al.
patent: 6964436 (2005-11-01), Le Quere
Banerjee, A. et al., “Preparation of a Monoclonal Antibody Specific for the Class IV Isotype of Beta-Tubulin. Purification and Assembly of Alpha-beta II, Alpha/beta III, and Alpha/beta IV Tubulin Dimers from Bovine Brain”J. Biol. Chem.(1992) 267(8):5625-5630, The American Society for Biochemistry and Molecular Biology, Inc. USA.
Banerjee, A. et al. “Differential Effects of Colchicine and its B-ring Modified Analog MTPT on the Assembly-independent BTPase Activity of Purified b-tubulin Isoforms from Bovine Brain,”Biochem. Biophys. Res. Commun.(1997) 231:698-700, Academic Press.
Chaudhuri, A.R. et al., “IKP104-Induced Decay of Tubulin: Role of the A-Ring Binding Site of Colchicine,”Biochemistry(1998) 37:17157-17162, American Chemical Society.
Khan, Israr A. et al., “Differential Interaction of Tubulin Isotypes with the Antimitotic Compound IKP-104,” (2000)Biochemistry39:9001-9009, American Chemical Society.
Lowry, O.H. et al., “Protein Measurement with the Folin Phenol Reagent”Biol. Chem.(1951) 193:265-275.
Lu, Q. et al., “Structural and Functional Properties of Tubulin Isotypes,” (1998)Adv. Struct. Biol.5:203-227, JAI Press Inc.
Lu, Q. et al., “In Vitro Analysis of Microtubule Assembly of Isotypically Pure Tubulin Dimers. Intrinsic Differences in the Assembly Process of Alpha/beta II, Alpha/beta III, and Alpha/beta IV Tubulin Dimers in the Absence of Microtubule-associated Proteins”J. Biol Chem.(1994) 269(3):2041-2047, The American Society for Biochemistry and Molecular Biology, Inc.
Panda et al., “Excimer Fluorescence of Pyrene-Maleimide-Labeled Tubulin”Eur. J. Biochm(1992) 204:783-787, FEBS 1992.
Panda et al. “Microtubule Dynamics in Vitro are Regulated by the Tubulin Isotype Composition,”Proc. Nat. Acad. Sci. USA(1994) 91:11358-11362.
Panda et al. “Stabilization of Microtubule Dynamics by Estramustine by Binding to a Novel Site in tubulin: A Possible Mechanistic Basis for its Antitumor Action”PNAS USA(1997) 94:10560-10564, The National Academy of Sciences.
Panda et al., “Suppression of Microtubule Dynamics by LY290181”J. Biol. Chem(1997) 272(12):7681-7687, The American Society for Biochemistry and Molecular Biology, Inc.
The Merck Index, p. 2438, Tenth Edition, Merck & Co., Inc., Rahway, New Jersey (1983).
Curry Stephen H.
Tuszynski Jack A.
Buchanan & Ingersoll & Rooney PC
Technology Innovations LLC
Witherspoon Sikarl A.
LandOfFree
Compositions and methods for the treatment of malaria does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Compositions and methods for the treatment of malaria, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions and methods for the treatment of malaria will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3740208