Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof
Patent
1979-05-17
1981-05-26
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Virus or component thereof
424272, A61K 31655, A61K 3142
Patent
active
042698308
ABSTRACT:
Compositions comprising substituted 5-nitroimidazoles and diminazene aceturate (Berenil) useful in the treatment of chronic trypanosomiasis infections in humans and animals. The substituted 2- or 5-nitroimidazoles having a 1-alkyl substituent and a 2-substituent, the latter being a .DELTA..sup.2 -4',5'-disubstituted isoxazoline. The 4',5'-substitution on the isoxazoline moiety is a saturated alkyl ring. Method of treatment of chronic trypanosomiasis infections in humans and animals by administering said compositions.
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Goldberg Jerome D.
Merck & Co. , Inc.
Rose David L.
Westlake Harry E.
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