Compositions and methods for the therapy and diagnosis of...

Details Compositions and methods for the therapy and diagnosis of... Compositions and methods for the therapy and diagnosis of...

2005-02-22

2005-02-22

Fredman, Jeffrey (Department: 1634)

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

C424S154100, C424S184100, C424S277100

Reexamination Certificate

active

06858204

ABSTRACT:
Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.

REFERENCES:
patent: 5589579 (1996-12-01), Torczynski et al.
patent: 1026242 (2000-08-01), None
patent: 1033401 (2000-09-01), None
patent: WO 9733993 (1997-09-01), None
patent: WO 9831799 (1998-07-01), None
patent: WO 9938973 (1999-08-01), None
patent: WO 0021990 (2000-04-01), None
patent: WO 0022130 (2000-04-01), None
patent: WO 0055375 (2000-09-01), None
patent: WO 0142451 (2001-06-01), None
patent: WO 0151628 (2001-07-01), None
Brinkmann et al, Cancer Research 59: 1445-1448 (Apr. 1999).*
Chen et al., “Isolation and characterization of a novel gene expressed in multiple cancers,”Oncogene 12(4):741-751, Feb. 15, 1996.
EMBL Database Accession No. AA948244, May 5, 1998.
EMBL Database Accession No. AA620697, Oct. 16, 1997.
GenBank Accession No. X21973, May 18, 1999.
Güre et al., “Human lung cancer antigens recognized by autologous antibodies: definition of a novel cDNA derived from the tumor suppressor gene locus on chromosome 3p21.3,”Cancer Research 58(1):1034-1041, Mar. 1, 1998.
Hara et al., “Characterization of cell phenotype by a novel cDNA library subtraction system: expression of CD8α in a mast cell-derived interleukin-4-dependent cell line,”Blood 84(1):189-199, Jul. 1, 1994.
Liu et al., “XAGE-1, a new gene that is frequently expressed in Ewing's sarcoma,”Cancer Research 60(17):4752-4755, Sep. 1, 2000.
Schena et al., “Quantitative monitoring of gene expression patterns with a complementary DNA microarray,”Science 270:467-470, Oct. 20, 1995.
Wu and Noguchi, “Activation of globin gene expression by cDNAs from induced K562 cells,”Journal of Biological Chemistry 266(26):17566-17572, Sep. 15, 1991.
Yee et al., “Isolation of tyrosinase-specific CD8+and CD4+T cell clones from the peripheral blood of melanoma patients following in vitro stimulation with recombinant vaccinia virus,”The Journal of Immunology 157:4079-4086, 1996.
EMBL Accession No. AA488696, Jul. 1, 1997.
EMBL Accession No. AW950090, Jun. 7, 2000.
EMBL Accession No. T63732.1, Mar. 5, 1995.
Hillier et al., “Generation and Analysis of 280,000 Human Expressed Sequence Tags,”Genome Research 6:807-828, 1996.
Zangemeister-Wittke and Stahel, “Novel approaches to the treatment of small-cell lung cancer,”CMLS. Cell. Mol. Life Sci. 55(12):1585-1598, Sep. 1999.
GenBank Database, Accession No. AAH09538, Oct. 22, 2001.
GenBank Database, Accession No. AJ318878, Jan. 14, 2002.
GenBank Database, Accession No. AJ318879, Jan. 14, 2002.
GenBank Database, Accession No. AJ400997, May 5, 2001.
GenBank Database, Accession No. BC009538, Oct. 22, 2001.
GenBank Database, Accession No. CAC38107, May 5, 2001.
GenBank Database, Accession No. CAC82986, Jan. 14, 2002.
GenBank Database, Accession No. CAC82987, Jan. 14, 2002.
GenBank Database, Accession No. AF251237, Aug. 23, 2000.
GenBank Database, Accession No. AAG01401, Aug. 23, 2000.
GenBank Database, Accession No. AJ290447, May 5, 2001.
GenBank Database, Accession No. CAC38108, May 5, 2001.
GenBank Database, Accession No. XM_010376, Oct. 16, 2001.
GenBank Database, Accession No. XP_010376, Oct., 16, 2001.
Geneseq Database (Derwent), Accession No. AAH64751, Sep. 11, 2001.
Geneseq Database (Derwent), Accession No. AAL13774, Dec. 7, 2001.
Geneseq Database (Derwent), Accession No. AAL22641, Dec. 7, 2001.
Geneseq Database (Derwent), Accession No. AAS37109, Dec. 17, 2001.

Affiliated with

Also associated with

Rating

Compositions and methods for the therapy and diagnosis of... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compositions and methods for the therapy and diagnosis of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions and methods for the therapy and diagnosis of... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3474227