Compositions and methods for the sublingual or buccal administra

Details Compositions and methods for the sublingual or buccal administra Compositions and methods for the sublingual or buccal administra

1992-11-30

1994-02-08

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424427, 424428, 424429, A61K 3754

Patent

active

052846571

ABSTRACT:
Pharmaceutical compositions for the sublingual or buccal administration of therapeutic agents (particularly polypeptides) which are normally degraded upon oral administration comprise such a therapeutic agent, a solvent, optionally a cosolvent and/or hydrogel, and an oral mucosal membrane transport enhancing agent which is selected from the group consisting of essential and volatile oils and inorganic and organic acids.

REFERENCES:
patent: 4244946 (1981-01-01), Rivier et al.
patent: 4382922 (1983-05-01), Rivier et al.
patent: 4632979 (1986-12-01), Coy et al.
patent: 4801577 (1989-01-01), Nestor, Jr. et al.

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