Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1996-07-16
1998-10-27
Sisson, Bradley L.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 911, 252700, 546102, 536 243, 536 2433, 536 253, 935 76, 935 77, C12Q 168, C09K 300, C07H 2104, C12N 1500
Patent
active
058276564
ABSTRACT:
The invention relates to methods for simultaneously or sequentially detecting multiple nucleic acid analytes in a single medium utilizing oligonucleotide hybridization probes coupled to different chemiluminescent labeling reagents. The methods may be used in a heterogeneous, homogeneous or non-homogeneous assay system. The invention also relates to specific combinations of chemiluminescent labeling reagents suitable, when coupled to an oligonucleotide probe, for use together in methods for the detection of multiple nucleic acid analytes. The invention also concerns kits useful in these methods.
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Cheikh Azzouz Ben
Nelson Norman Charles
Weeks Ian
Woodhead James Stuart
Fisher Carlos A.
Gen-Probe Incorporated
Sisson Bradley L.
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