Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1995-02-28
1997-06-03
Saunders, David
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 75, 435 2, 530395, 530868, C07K 1474, G01N 33566
Patent
active
056353634
ABSTRACT:
T cells are specifically labeled according to their antigen receptor by binding of a multimeric binding complex. The complex is prepared with major histocompatibility complex protein subunits having a homogeneous population of peptides bound in the antigen presentation site. The multimeric MHC-antigen complex forms a stable structure with T cells, thereby allowing for the labeling, identification and separation of specific T cells.
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Invention Disclosure: Altman, et al., Detection, Enumeration and Purification of Antigen-Specific T Cells (Dec. 29, 1993) Stanford University, Stanford, CA.
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Altman John D.
Davis Mark M.
McHeyzer-Williams Michael G.
Saunders David
Sherwood Pamela J.
The Board of Trustees of the Leland Stanford Junior University
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