Compositions and methods for the control of flukes

Details Compositions and methods for the control of flukes Compositions and methods for the control of flukes

1991-03-27

1993-11-16

Wax, Robert A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

424 93L, 424405, 530350, A61K 3700, A01N 2500

Patent

active

052623998

ABSTRACT:
Methods and compositions for the control of flukes are described. Specifically, Bacillus thuringiensis (B.t.) isolates having flukicidal activity are disclosed. Also described are recombinant hosts which express B.t. genes coding for flukicidal toxins. The B.t. isolates and recombinant proteins are shown to be useful in a method for controlling flukes including the liver fluke.

REFERENCES:
patent: 4948734 (1990-08-01), Edwards et al.
patent: 5093120 (1992-03-01), Edwards et al.
Bottjer, K. P., L. W. Bone, S. S. Gill, (1985), "Nematoda: Susceptibility of the Egg to Bacillus thuringiensis Toxins", Exp. Parasitol., 60:239-244.
Ignoffo, C. M., V. H. Dropkin, (1977), "Deleterious Effects of the Thermostable Toxin of Bacillus thuringiensis on Species of Soil-Inhabiting, Myceliophagous, and Plant-Parasitic Nematodes", J. Kansas Entomological Soc., 50(3):394-398.
Ciordia, H., W. E. Bizzell, (1961), "A Preliminary Report of the Effects of Bacillus thuringiensis var. thuringienesis on the Development of the Free-Living Stages of Some Cattle Nematodes", J. Parasitol., 47:41 (abstract).

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