Compositions and methods for the acceleration of protein...

Details Compositions and methods for the acceleration of protein... Compositions and methods for the acceleration of protein...

2007-07-31

2007-07-31

Zara, Jane (Department: 1635)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C435S006120, C435S091100, C435S455000, C536S023100, C536S023500, C536S023510, C536S024100, C536S024500

Reexamination Certificate

active

10419539

ABSTRACT:
The present invention provides compositions and methods for modulating the secretion of transcriptionally regulated proteins from recombinant cells. More particularly, the present invention provides compositions and methods for accelerating the secretion dynamics of human insulin from recombinant cells using nonsense mediated mRNA decay of the preproinsulin mRNA transcript.

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