Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...
Reexamination Certificate
2004-11-15
2010-02-02
Sajjadi, Fereydoun G (Department: 1633)
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Introduction of a polynucleotide molecule into or...
C424S093200, C514S04400A
Reexamination Certificate
active
07655467
ABSTRACT:
The present invention provides systemic nucleic acid sequence delivery without conventional systemic administration aids (SAAs). In certain embodiments, vascular permeability agents (VPAs), such as VEGF, are used in conjunction with nucleic acid viral vectors, such as adeno-associated virus (AAV). The present invention also provides methods of treating disease by co-administration of nucleic cid sequences encoding Igf-1 and dystrophin or dystrophin-like proteins.
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Allen James M.
Blankinship Michael J.
Chamberlain Jeffrey S.
Gregorevic Paul
Casimir Jones S.C.
Sajjadi Fereydoun G
The University of Washington
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