Compositions and methods for siRNA inhibition of...

Details Compositions and methods for siRNA inhibition of... Compositions and methods for siRNA inhibition of...

2011-08-09

2011-08-09

Chong, Kimberly (Department: 1635)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S024100, C536S024310, C435S006120, C435S325000, C435S375000, C514S04400A

Reexamination Certificate

active

07994305

ABSTRACT:
RNA interference using small interfering RNAs which are specific for mRNA produced from the Ang1, Ang2 or Tie2 genes inhibits expression of these genes. Diseases which involve Ang1, Ang2 or Tie2 mediated angiogenesis, such as inflammatory and autoimmune diseases, diabetic retinopathy, age related macular degeneration and many types of cancer, can be treated by administering the small interfering RNAs.

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