Compositions and methods for screening drug libraries

Details Compositions and methods for screening drug libraries Compositions and methods for screening drug libraries

1996-04-03

1999-02-02

Achutamurthy, Ponnathapura

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Using a micro-organism to make a protein or polypeptide

435 4, 435 5, 435 6, 435 72, 435 792, G01N 3353

Patent

active

058663410

ABSTRACT:
A method of screening for binding partners of a specific molecule. The method employs a chimeric protein having at least two different binding regions; one containing at least a portion of the specific molecule or an analog thereof, and the other containing a binding region of an immunoglobulin chain. In a preferred embodiment, the method is used for rapidly screening member compounds of a combinatorial library for potential biological activity.

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