Compositions and methods for reparation and prevention of fibrot

Details Compositions and methods for reparation and prevention of fibrot Compositions and methods for reparation and prevention of fibrot

1996-05-09

1998-02-10

Spear, James M.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424427, 424434, 424435, 424436, 424451, 424464, 424489, 514838, 514866, 514879, 514913, 514824, A61K 902, A61K 914, A61K 920, A61K 948

Patent

active

057166323

ABSTRACT:
In a preferred embodiment, drugs having pharmacological properties which are useful in the medicinal therapy of fibrotic disease for the reparation and prevention of fibrotic lesional tissues, such drugs including as active ingredient(s) one or more N-substituted 2-(1H) pyridone(s) and/or N-substituted 3-(1H) pyridones. The composition of this invention is novel as an anti-fibrotic drug, namely, as an agent for treating fibrosis. Any existing compounds have not been shown to be effective for the reparation and prevention of fibrotic lesions.

REFERENCES:
patent: 5310562 (1994-05-01), Margolin
patent: 5518729 (1996-05-01), Margolin

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