Compositions and methods for removing heavy metals from...

Details Compositions and methods for removing heavy metals from... Compositions and methods for removing heavy metals from...

2007-09-25

2007-09-25

Wax, Robert A (Department: 1656)

Hazardous or toxic waste destruction or containment

Processes for making harmful chemical substances harmless,...

By reacting with chemical agents

C261S001000, C405S128500, C435S289100, C588S412000

Reexamination Certificate

active

11255427

ABSTRACT:
Devices, such as solid supports having metal binding proteins, such as metallothionein proteins, bound thereto are disclosed for removing metals from substrates in need of having such metals removed therefrom. Specifically membranes having metallothionein proteins from the brine shrimpArtemiaare disclosed for removing metals from liquid substrates. Associated methods for removing metals from substrates using metallothionein proteins are also disclosed.

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Brook et al., Purification of metallothionein-like metal binding proteins from Artemia. Molecular Biology of the Cell. 1994, vol. 5, No. Suppl, p. 226A, Abstract No. 1316
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“NOTICE” regarding publication developed under Grant No. CX824823 awarded by the U.S. EPA.
Pedersen et al., Primary structures of decapod crustacean metallothioneins with special emphasis on freshwater and semi-terrestrial species. Biochemistry Journal 1996, vol. 319, pp. 999-1003.
Ma et al., Recent Developments for in situ treatment of metal contaminated soils. Prepared for U.S. EPA by PRC Management Inc., dated Mar. 5, 1997 and published on web site at http://www.clu-in.org//download/remed/metals2.pdf.
Evanko et al., Remediation of metals—contaminated soils and groundwater. Technology Evaluation Report prepared for GWRTAC dated Oct. 1997.
Valls et al., Engineering a mouse metallothionein on the cell surface ofRalstonia europhaCH34 for immobilization of heavy metals in soil. Nature Biotechnology. 2000, vol. 18 pp. 661-665.
Del Ramo et al., Effect of cadmium pre-exposure in cadmium accululation by brine shrimp Artemia: involvement of low-molecular-weight cadmium-binding ligands. Marine Environmental Research 1993 vol. 5. pp. 29-33.
Sode et al., Construction of a marine cyanobacterial strain with increased heavy metal ion tolerance by introducing exogenic metallothionein gene. Journal of Marine Biotechnology 1998 vol. 6 pp. 174-177.
Brook et al., Purification of metallothionein-like metal binding proteins from Artemia. Molecular Biology of the Cell. 1994, vol. 5, No. Suppl, p.226A, Abstract No. 1316.
Chen et al., The induction and extraction of metallothioneins in Artemia. Chinese Journal of Oceanology and Limnology. 1994, vol. 12, No. 2 pp. 175-179, especially pp. 177-178.
Fischer et al., Recent excitement regarding metallothionein. Proceeding of the National Academy of Sciences USA. 1998, vol.95 pp. 333-334.
Hammer, Metallothionein. Annual Review of Biochemistry. 1986, vol. 55, pp. 913-951.
“Notice” regarding publication developed under Grant No. CX824823 awarded by the U.S. EPA.
Pedersen et al., Primary structures of decapod crustacean metallothioneins with special emphasis on freshwater and semi-terrestrial species. Biochemistry Journal 1996, vol. 319, pp. 999-1003.
Ma et al., Recent Developments for in situ treatment of metal contaminated soils. Prepared for U.S. EPA by PRC Management Inc., dated Mar. 5, 1997 and published on web site at http://www.clu-in.org//download/remed/metals2.
Evanko et al., Remediation of metals-contaminated soils and groundwater. Technology Evaluation Report prepared for GWRTAC dated OCT., 1997.
Valls et al., Engineering a mouse metallothionein on the cell surface of Ralstonia europha CH34 for immobilization of heavy metals in soil. Nature Biotechnology. 2000, vol. 18 pp. 661-665.
Del Ramo et al., Effect of cadmium pre-exposure in cadmium accululation by brine shrimp Artemia: Involvement of low-molecular-weight cadmium-binding ligands. Marine Environmental Research 1993 vol. 5, pp. 29-33.
Sode et al., Construction of a marine cyanobacterial strain with increased heavy metal ion tolerance by introducing exogenic metallothionein gene. Journal of Marine Biotechnology 1998 vol. 6 pp. 174-177.
Chen et al. “Hg2+ removal by genetically engineered Escherichia coli in a hollow fiber reactor,” Biotechnol. Prog. 14:667-71, 1998.
Bae et al. “Enhanced bioaccumulation of heavy metals by bacterial cells displaying synthetic phytochelatins,” Biotechnology and Bioengineering. 70:518-524, 2000.

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