Compositions and methods for regulating RNA stability using...

Details Compositions and methods for regulating RNA stability using... Compositions and methods for regulating RNA stability using...

2007-07-03

2007-07-03

Mondesi, Robert B. (Department: 1652)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

C435S007100, C435S069100

Reexamination Certificate

active

11389947

ABSTRACT:
Compositions and methods for regulating CD154 gene expression are provided that rely on the interaction of polypyrimidine tract proteins with the 3′-untranslated region of CD154.

REFERENCES:
Gil et al., “Characterization of cDNAs encoding the polypyrimidine tract-binding protein”, Genes & Development 1992 5:1224-1236.
Markovtsov et al., “Cooperative Assembly of an hnRNP Complex Induced by a Tissue-Specific Homolog of Polypyrimidine Tract Binding Protein”, Molecular and cellular Biology 2000 20(20):7463-7479.
Patton et al., “Characterization and molecular cloning of polypyrimidine tract-binding protein:a component of a complex necessary for a pre-mRNA splicing”, Genes & Development 1991 5:1237-1251.
Strasburg et al., “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”, Proc. Natl. Acad. Sci. USA 2002 99(26):16899-16903.

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