Compositions and methods for regulating bacterial pathogenesis

Details Compositions and methods for regulating bacterial pathogenesis Compositions and methods for regulating bacterial pathogenesis

2005-08-30

2005-08-30

Smith, Lynette R. F. (Department: 1645)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving viable micro-organism

C435S029000, C435S007320, C435S007100, C435S006120, C435S252100, C435S252300, C514S046000, C536S115000

Reexamination Certificate

active

06936435

ABSTRACT:
The production of a purified extracellular bacterial signal called autoinducer-2 is regulated by changes in environmental conditions associated with a shift from a free-living existence to a colonizing or pathogenic existence in a host organism. Autoinducer-2 stimulates LuxQ luminescence genes, and is believed also to stimulate a variety of pathogenesis related genes in the bacterial species that produce it. A new class of bacterial genes is involved in the biosynthesis of autoinducer-2.

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