Compositions and methods for regulating autolytic processes...

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Nucleoproteins – e.g. – chromatin – chromosomal proteins,...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C530S350000, C536S024100, C536S024200

Reexamination Certificate

active

07148328

ABSTRACT:
A nucleic acid sequence required for regulating the autolytic activity of bacteria is provided. Also provided are polypeptides encoded by the gene or mutant gene as well as vector and host cells for expressing these polypeptides. Methods for identifying and using agents which interact with the gene or mutant gene or polypeptides encoded thereby to inhibit bacterial growth and infectivity are also provided.

REFERENCES:
Fournier et al. (Journal of Bacteriology, 2000, vol. 182, No. 14, pp. 3955-3964).
Fujimoto et al. (Journal of Bacteriology, 2000, vol. 182, No. 14, pp. 4822-4828).
Watson et al “Molecular Biology of the Gene” 4th Edition (1987) Benjamin-Cummings Publishing Company, Inc. USA, p. 608.
Foster S.J., “Molecular Characterization and Functional Analysis of the Major Autolysin ofStaphylococcus aureus8325/4”, Journal of Bacteriology 1995 177(19):5723-2725.
Ramadurai et al., “Molecular Cloning, Sequencing, and Expression oflytM, a Unique Autolytic Gene ofStaphylococcus aureus”, Journal of Bacteriology 1997 179(11):3625-3631.
Rice et al., “Description of Staphylococcus Serine Protease (ssp) Operon inStaphylococcus aureusand Nonpolar Inactivation of sspA-Encoded Serine Protease”, Infection and Immunity 2001 69(1):159-169.
Schrader-Fischer et al., “The AbcA Transporter ofStaphylococcus aureusAfflects Cell Autolysis”, Antimicrobial Agents and Chemotherapy 2001 45(2):407-412.
Pan et al., “Cloning and Characterization of theparCandparEGenes ofStreptococcus pneumoniaeEncoding DNA Topoisomerase IV:Role in Fluroquinolone Resistance”, J. Bacteriology 1996 178(14):4060-4069.
NCBI Genome Project—Complete Microbial Genomes [A]-25, [B]-269.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Compositions and methods for regulating autolytic processes... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compositions and methods for regulating autolytic processes..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions and methods for regulating autolytic processes... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3710317

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.