Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-07-19
2005-07-19
Weddington, Kevin E. (Department: 1614)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S012200, C514S255040, C514S317000, C514S331000
Reexamination Certificate
active
06919350
ABSTRACT:
A method of reducing, treating or preventing drug-mediated respiratory depression, muscle rigidity, or nausea/vomiting in an animal, incident to the administration to said animal of a mixed delta/mu opioid agonist or a respiratory depression-mediating drug, comprising administering to the animal receiving said drug an effective amount of a delta receptor agonist compound. Preferred examples of such delta receptor agonist compound include diarylmethyl piperazine compounds and diarylmethyl piperidine compounds, and pharmaceutical compositions thereof, having utility in medical therapy for reducing respiratory depression associated with certain analgesics, such as mu opiates.
REFERENCES:
patent: 5552404 (1996-09-01), Chang et al.
patent: 5574159 (1996-11-01), Chang et al.
patent: 5658908 (1997-08-01), Chang et al.
patent: 5681830 (1997-10-01), Chang et al.
patent: 5807858 (1998-09-01), Chang et al.
patent: 5854249 (1998-12-01), Chang et al.
patent: 5968551 (1999-10-01), Oshlack et al.
patent: 5985880 (1999-11-01), Chang et al.
patent: 6200978 (2001-03-01), Maw et al.
patent: 6300332 (2001-10-01), Chang et al.
patent: 208633 (1994-05-01), None
patent: 218673 (2000-10-01), None
patent: WO 98/52929 (1998-11-01), None
Database CAPLUS on STN, Dep. Pharmacology, University Michigan, (Ann Arbor, MI), Document No. 121:271967, Negus, S. et al., “Behavioral effects of the systematically active delta opioid agonist BW373U86 in rhesus monkeys,” abstract, J. Pharmacol. Exp. Ther., 270(3), 1025-1034, 1994.
Bishop Michael J.
Chang Kwen-Jen
McNutt, Jr. Robert W.
Pettit Hugh O.
Ardent Pharmaceuticals, Inc.
Fuierer Marianne
Hultquist Steven J.
Weddington Kevin E.
LandOfFree
Compositions and methods for reducing respiratory depression... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Compositions and methods for reducing respiratory depression..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions and methods for reducing respiratory depression... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3376567