Compositions and methods for reducing blood and fluid loss...

Details Compositions and methods for reducing blood and fluid loss... Compositions and methods for reducing blood and fluid loss...

2007-12-04

2007-12-04

Ghali, Isis (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

C424S449000, C424S448000

Reexamination Certificate

active

10178448

ABSTRACT:
The invention described herein relates to methods for reducing and/or stopping bleeding or fluid loss from open wound, denuded tissue, or burned skin, comprising the step of applying to the open wound, denuded tissue or burned skin a gel-forming composition comprising at least one of the following compositions: a polyacrylic acid having the structural formula [CH2═CHCO2H]n, where n is between 10,000 and 70,000; a polyacrylic acid and a desiccated water soluble organic or inorganic base; polyacrylic acid and a desiccated poorly soluble basic salt, and a polyvinyl alcohol having the structural formula of [CH2═CHOH]n, where n is between 15,000 and 150,000. When the gel-forming composition is applied to the open wound, denuded tissue, or burned skin, its ions react therein in the presence of water from blood or body fluid therein to form an aqueous gel or mucilage having sufficient viscosity and adhesiveness to cover and adhere to the open wound, denuded tissue, or burned skin so that bleeding or fluid loss is thereby reduced and/or stopped.

REFERENCES:
patent: 4552138 (1985-11-01), Hofeditz et al.
patent: 4822349 (1989-04-01), Hursey et al.
patent: 4920158 (1990-04-01), Murray et al.
patent: 5260066 (1993-11-01), Wood et al.
patent: 5457093 (1995-10-01), Cini et al.
patent: 5578661 (1996-11-01), Fox et al.
patent: 5858350 (1999-01-01), Vournakis et al.
patent: 5891074 (1999-04-01), Cesarczyk
patent: 6060461 (2000-05-01), Drake
patent: 6133326 (2000-10-01), Mayne
patent: 6187347 (2001-02-01), Patterson et al.
patent: 6399092 (2002-06-01), Hobson et al.
patent: 6531500 (2003-03-01), Farber
patent: 6559350 (2003-05-01), Tetreault et al.
patent: 6723781 (2004-04-01), Frate et al.
Clinical Studies: FirstSTOP, by VasoSeal, from internet website http://www.vasoseal.com/sh/shclinical.html, 2001.
Catrix Wound Dressing, by Catrix Science & Nature, from internet website http:///www.catrix.com/products/wound—dressing/html., 1997.
Ferber et al., “Case Report: Interactive wet therapy with TenderWet—three years clinical experience with chronic wounds”, published at internet website http://www.hartmann-online.de/english/produkte/wunderbehandling/wunderforum/4-95-2.html, Apr. 4, 1995 (6 pages).
Kocak et al., “Comparative Efficacy of Topical SodiumHyaluronate in Renal Trauma Model”, published at internet website http://www.brazjurol.com.br/maio—2001/Kocak—289—294.html, 2001 (6 pages).
PR Newswire Magazine, “Focal, Inc. Receives U.S. Government Grant to Study Use of FocalSEal Technology in Carpal Tunnel Surgery”, published at internet website http://www.findarticles.com/cf—o/m4PRN/1998?Sept/21/53.../article.html, Sep. 21, 1998 (2 pages).
Hemaseel APR, Haemacure Products, published internet website http://www.haemacure.com/en/products/hemaseelAPR.html, referencing product launch in June of 1998 (1 page).
“Closure Medical closes distribution deal,” The Business Journal, published at internet website http://trangle.bizjournals.com/trinalge/stories/2001/07/16/daily13.html, Jul. 17, 2001 (2 pages).
Johnson & Johnson, News, “Johnson & Johnson Has You Covered—Presenting Three New Bandages to Protect Wounds”, published at internet website http://www.jnj.com
ews/jnj—news/20020308—1047.html, Mar. 12, 2001 (2 pages).
“Closure Medical Corporation (CLSR) Signs Definitive Agreement with Johnson & Johnson Companies, Inc. For Its Liquiderm Liquid Adhesive Bandage”, published at internet website http://www.biospace.com/ccis
ews—story.cfm, May 29, 2001 (2 pages).
Notice in Popular Science Magazine, Jun. 2001, “Blood is Thicker with Seawater”, p. 14.
Sugg, Diane, “Bandage stanches bleeding in seconds”, published in The Sun, Saturday edition, Oct. 17, 1998, pp. 1A and 5A.
International Search Report for International patent application No. PCT/US02/19554 (filed Jun. 20, 2002) (parallel PCT case to instant US case), dated Feb. 26, 2003 (2 pages).

Affiliated with

Also associated with

Rating

Compositions and methods for reducing blood and fluid loss... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compositions and methods for reducing blood and fluid loss..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions and methods for reducing blood and fluid loss... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3829828