Compositions and methods for nucleus pulposus regeneration

Details Compositions and methods for nucleus pulposus regeneration Compositions and methods for nucleus pulposus regeneration

2011-03-01

2011-03-01

Kemmerer, Elizabeth C. (Department: 1646)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

C424S425000, C424S426000, C514S001100, C514S016700, C514S020900, C514S021200, C514S007600, C514S008200, C514S008500, C514S008800, C514S008900

Reexamination Certificate

active

07897164

ABSTRACT:
Compositions for nucleus pulposus regeneration is provided. Such composition may comprise a scaffolding material and a pore creating agent dispersed within the scaffolding material. The pore creating agent is removed from the scaffolding material in vivo, after the composition is administered to a patient. The pore creating agent may include an active agent, such as a growth factor, which may be released as the pore creating agent is being gradually removed from the scaffolding material. In addition, removal of the pore creating agent results in a porous scaffold for cells capable of regeneration of nucleus pulposus, either existing in situ or delivered separately, to attach to for further proliferation and regeneration.

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