Chemistry: analytical and immunological testing – Thyroid hormone tests
Patent
1987-06-08
1991-03-19
Nucker, Christine
Chemistry: analytical and immunological testing
Thyroid hormone tests
436505, 436538, 436539, 436540, 436542, 436545, 436548, 436804, 530389, 530402, G01N 33534
Patent
active
050010727
ABSTRACT:
Compositions and methods are disclosed for multiple simultaneous assays of different analytes using radioactive labeled antibodies to the analytes, at least one portion of the assay being an immunoradiometric assay in which there is employed a metal isotope label, e.g., .sup.57 Co, attached to an antibody to the analyte through a chelator, e.g., ethylenediaminetetraacetic acid. Multiple simultaneous immunoradiometric assays can be performed by this method, as can multiple simultaneous assays in which one portion of the assay is an immunoradiometric assay and another portion or portions involve one or more other radioassay techniques.
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Meares et al. "Covalent Attachment of Metal Chelates to Proteins: The Stability in Vivo and in Vitro of the Conjugate of Albumin with a Chelate of .sup.111 Indium"; Proc. Natl. Acad. Sci., U.S.A., 73(11), 1976, 3803-3806.
ICN Biomedicals Inc.
Nucker Christine
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