Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals
Reexamination Certificate
2007-01-23
2007-01-23
Navarro, Mark (Department: 1645)
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
C436S165000, C436S172000, C436S525000, C436S527000, C356S317000, C356S318000, C422S051000
Reexamination Certificate
active
09259658
ABSTRACT:
This invention relates to a method for analyzing a sample comprising: immobilising a polypeptide to a physical support; contacting the immobilised polypeptide with a test sample which may contain an agent capable of modifying the immobilised polypeptide; contacting the immobilised polypeptide with a binding partner polypeptide, wherein the binding of this partner polypeptide to the immobilised polypeptide is at least partly dependent on the modification state of the immobilised polypeptide; and measuring the association of the binding partner polypeptide to the immobilised polypeptide.
REFERENCES:
patent: 4478934 (1984-10-01), Sato et al.
patent: 5082786 (1992-01-01), Nakamoto
patent: 5185248 (1993-02-01), Barbacid et al.
patent: 5194393 (1993-03-01), Hugl et al.
patent: 5208111 (1993-05-01), Decher et al.
patent: 5215887 (1993-06-01), Saito
patent: 5225064 (1993-07-01), Henkens et al.
patent: 5316754 (1994-05-01), Vlassara et al.
patent: 5341215 (1994-08-01), Seher
patent: 5416003 (1995-05-01), Lawrence et al.
patent: 5439797 (1995-08-01), Tsien et al.
patent: 5478755 (1995-12-01), Attridge et al.
patent: 5484735 (1996-01-01), Davis et al.
patent: 5565352 (1996-10-01), Hochstrasser et al.
patent: 5578477 (1996-11-01), Tamanoi
patent: 5582995 (1996-12-01), Avruch et al.
patent: 5605152 (1997-02-01), Slate et al.
patent: 5631169 (1997-05-01), Lakowicz et al.
patent: 5637463 (1997-06-01), Dalton et al.
patent: 5682884 (1997-11-01), Hill et al.
patent: 5710009 (1998-01-01), Fitzpatrick et al.
patent: 5736337 (1998-04-01), Avruch et al.
patent: 5744313 (1998-04-01), Williams et al.
patent: 5753436 (1998-05-01), Bronstein et al.
patent: 5755953 (1998-05-01), Henning et al.
patent: 5763571 (1998-06-01), Avruch et al.
patent: 5767075 (1998-06-01), Avruch et al.
patent: 5773592 (1998-06-01), Mills
patent: 5776717 (1998-07-01), Cao
patent: 5789541 (1998-08-01), Rando
patent: 5795729 (1998-08-01), Lee
patent: 5837478 (1998-11-01), Gallatin et al.
patent: 5837822 (1998-11-01), Gallatin et al.
patent: 5849174 (1998-12-01), Sanghera et al.
patent: 5849495 (1998-12-01), Bronstein et al.
patent: 5851791 (1998-12-01), Vierstra et al.
patent: 5863726 (1999-01-01), Harley et al.
patent: 5880268 (1999-03-01), Gallatin et al.
patent: 5891638 (1999-04-01), Ibanez et al.
patent: 5932421 (1999-08-01), Ginsberg et al.
patent: 5948620 (1999-09-01), Hurd et al.
patent: 5962289 (1999-10-01), Kilburn et al.
patent: 5962637 (1999-10-01), Shone et al.
patent: 5965699 (1999-10-01), Schmidt et al.
patent: 5965789 (1999-10-01), Lubon et al.
patent: 5976815 (1999-11-01), Ibanez et al.
patent: 5977303 (1999-11-01), Aversa et al.
patent: 5981167 (1999-11-01), Taremi et al.
patent: 5981200 (1999-11-01), Tsien et al.
patent: 5989843 (1999-11-01), Gallatin et al.
patent: 5990277 (1999-11-01), Levitzki et al.
patent: 6001619 (1999-12-01), Beach et al.
patent: 6010848 (2000-01-01), Delvecchio et al.
patent: 6037136 (2000-03-01), Beach
patent: 6103692 (2000-08-01), Avruch et al.
patent: 6110691 (2000-08-01), Wang et al.
patent: 6117641 (2000-09-01), Berlin et al.
patent: 6140067 (2000-10-01), Anderson et al.
patent: 6146842 (2000-11-01), Josiah et al.
patent: 6235466 (2001-05-01), Branch et al.
patent: 6242173 (2001-06-01), Mann et al.
patent: 6243980 (2001-06-01), Bronstein et al.
patent: 6251621 (2001-06-01), Lawrence et al.
patent: 6261793 (2001-07-01), Whyte et al.
patent: 6268123 (2001-07-01), Faff
patent: 6322970 (2001-11-01), Little et al.
patent: 6410255 (2002-06-01), Pollok et al.
patent: 6475809 (2002-11-01), Wagner et al.
patent: 6569833 (2003-05-01), Fahraeus et al.
patent: 6573094 (2003-06-01), Harper et al.
patent: 6613878 (2003-09-01), Cox et al.
patent: 6630311 (2003-10-01), Epps et al.
patent: 6682898 (2004-01-01), Wu et al.
patent: 6682942 (2004-01-01), Wagner et al.
patent: 6714875 (2004-03-01), Nash et al.
patent: 6808874 (2004-10-01), Griffiths
patent: 6810362 (2004-10-01), Adachi et al.
patent: 2003/0104504 (2003-06-01), Colyer et al.
patent: 0392808 (1990-10-01), None
patent: 628819 (1994-12-01), None
patent: 90/14431 (1990-11-01), None
patent: WO95/34646 (1995-12-01), None
patent: WO96/20211 (1996-07-01), None
patent: WO96/21040 (1996-07-01), None
patent: WO96/35806 (1996-11-01), None
patent: WO97/28261 (1997-08-01), None
patent: WO97/44481 (1997-11-01), None
patent: WO9820024 (1998-05-01), None
patent: WO98/39471 (1998-09-01), None
patent: 9911774 (1999-03-01), None
patent: WO99/11774 (1999-03-01), None
Manne, V et al, Drug Development REsearch, vol. 34, 1995, pp. 121-137, Ras farnesylation as a target for novel antitumor agents:Potent and selective farnexyl diphosphate analog inhibitors of farnesyltransferase.
SpA scintillation proximity assay, Cytostar-T scintillating microplate, Nov. 1997, Issue No. 35, Proximity News, Scintillation Proximity Assay (SPA) Bibliography, Amersham Life Science,pp. 1-8, listing of references for protein-protein interactions.
Leftheris, K et al, J. Med. Chem, 1996, vol. 39, pp. 224-236, Developmnet of Highly Potent Inhibitors of Ras Farnesyltransferase Processing and in vivo activity.
Kohl, Nancy E., Farnesyltransferase Inhibitors, Preclinical Development, pp. 91-102, Annals New York Academy of Sciences, 1999, vol. 886.
Omer, CA et al, Ca1A2X-competitive inhibitors of farnesyltransferase as anti-cancer agents, TIPS, Nov. 1997, vol. 18, pp. 437-445.
Qian, Y et al, Farnesyltransferase as a target for anticancer drug design, Biopoly, vol. 43, pp. 25-41, 1997.
Lebowitz, Peter F. et al, Molecular and Cellular Biology, Dec. 1995, vol. 15(12), pp. 6613-6622, Evidence that Farnesyltransferase inhibitors suppress RAs transformation by interfering with Rho activity.
Avruch, J et al, The Endocrine Society, pp. 127-155, Recent progress in Hormone Research, vol. 56,Ras activation of the Raf kinase (abstract only).
Adler, et al.,in Methods in Enzymology, 27:675-796 (1973).
Atherton, et al.,J. Chem. Soc., 538-546 (1981).
Biou, et al.,Science, 263:1404-1410 (1994).
Blenis and Erikson,Proc. Natl. Acad Sci. USA, 82:7621-7625 (1985).
Carrington, et al.,Journal of Virology, 62:2313-2320 (1988).
Casey and Seabra,J. Biol. Chem., 271:5289-5292 (1996).
Cesareni, er al.,Proc. Natl. Acad. Sci. USA, 79:6313-6317 (1982).
Cox,Methods Enzymol., 250:105-121 (1995).
Crick,Acta. Cyrstallogr., 6:689-697 (1953).
Drago and Colyer,J. Biol. Chem., 269:25073-25077 (1994).
Fushman, et al.,J. Biol. Chem., 273:2835-2843 (1998).
Gonzalez, et al.,Nature Structural Biol., 3:1011-1018 (1996).
Hahn, et al.,PNAS(USA), 89, 2679-2683 (1992).
Haltiwanger, et al.,J. Biol. Chem., 265:2563-2568 (1990).
Hanson and Schulman,Ann. Rev. Biochem., 61:559 (1992).
Harbury, et al.,Nature, 371:80-83 (1994).
Härtlein, er al.,Nucleic Acids Res., 15:1005-1017 (1987).
Hattori, et al.,Proc. Natl. Acad. Sci. USA, 85:9148-9152 (1988).
Hayashi, et al.,J. Biol. Chem., 248:2296-2302 (1973).
Hicks, et al.,Folding and Design, 2:149-158 (1997).
Hinnebusch,Proc. Natl. Acad. Sci. USA, 81:6442-6446 (1982).
Horiuchi, et al.,Mol. Cell. Biol., 12:4515 (1992).
Itoh, et al.,J. Biol. Chem., 268:3025 (1993).
Jovin and Jovin,Cell Structure and Function by Microspectrofluorometry, Kohen and Hirschberg, eds., Academic Press (1989).
Kemp and Pearson,TIBS, 15:342-346 (1990).
Klauck, et al.,Science, 271:1589-1592 (1996).
Konishi, et al.,Biochem. Biophys. Res. Comm., 205:1770-1775 (1994).
Lakowicz,Principles of Fluorescence Spectroscopy, Plenum Press, NY (1983).
Larsson and Cerutti,J. Biol. Chem., 263:17452-17458 (1988).
Lovejoy, et al.,Science, 259:1288-1293 (1993).
Lumb and Kim,Biochemistry, 34:8642-8648 (1995).
Lumb, et al.,Biochemistry, 33:7361-7367 (1994).
Matthias, et al.,Nucl. Acids Res., 17:6418 (1989).
Mátyus,J. Photochem. Photobiol. B.:Bio., 12:323-337 (1992).
Merrifield,J. Am. Chem. Soc., 85:2149-2154 (1963).
Miller,Ann. Rev. Microbiol., 42:177-199 (1988).
Milligan, et al.,Trends in Biochemical Sciences, 20:181-186 (1995).
Nautiyal, et al.,Biochemistry, 34:11645-11651 (1995).
Nemenoff, et al.,Arch. Biochem. Biophys., 245:196-203 (1986).
Novak-Hofer and Thomas,J. Biol. Chem., 259:5995-6000 (1984).
O'Shea, et al.,Science, 243:538-542 (
Colyer John
Craig Roger K.
Maschio Antonio
Mezna Mokdad
Cyclacel Ltd.
Edwards Angell Palmer & Dodge
Navarro Mark
Portner Ginny Allen
Spar Elizabeth N.
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