Compositions and methods for modulating cell proliferation using

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Solid support and method of culturing cells on said solid...

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435383, 435384, 435385, 435386, 435387, 530350, 530351, 5303871, 530399, 514 2, C07K 1400, C12N 502

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058743081

ABSTRACT:
Methods and compositions are provided for in vitro expansion of growth factor dependent cells. Expansion is effected through the use of growth factor conjugates that include a growth factor such as a steel factor and a polysaccharidase substrate binding region. The conjugates are immobilized by binding of the substrate binding region to a substrate of the polysaccharidase in a growth chamber for the cells.

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