Compositions and methods for management of diabetes

Details Compositions and methods for management of diabetes Compositions and methods for management of diabetes

2011-08-09

2011-08-09

Tate, Christopher R. (Department: 1655)

Drug, bio-affecting and body treating compositions

Plant material or plant extract of undetermined constitution...

Containing or obtained from a seed or nut

C424S725000

Reexamination Certificate

active

07993687

ABSTRACT:
A buckwheat extract comprising at least myo-inositol, D-chiro-inositol, a fagopyritol, one MAPK-stimulating compound, and one glucose-uptake inhibiting compound. A substantially pure glucose-uptake inhibiting compound selected from a buckwheat extract. A method for providing a glucose-uptake inhibiting extract from buckwheat seed comprising first contacting said buckwheat seed with a non-polar solvent, then contacting said buckwheat seed with a polar aprotic solvent, and then finally contacting said buckwheat seed with a third solvent. The third solvent may be a polar aprotic solvent or a polar protic solvent. The extract produced by contacting buckwheat seed with the third solvent is dried to remove the solvent therefrom. Compositions comprising dried glucose-uptake inhibiting buckwheat extracts and purified compounds therefrom.

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Julianne M. Kawa, Carla G. Taylor, and Roman Przybylski (2003) Buckwheat Concentrate Reduces Serum Glucose in Streptozotocin-Diabetic Rats. J. Agric. Food Chem. 51: 7287-729.

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