Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving cholesterol
Reexamination Certificate
2007-10-09
2007-10-09
Gitomer, Ralph (Department: 1657)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving cholesterol
Reexamination Certificate
active
11305675
ABSTRACT:
Provided herein are compositions and methods for lipoprotein uptake assay. These compositions and methods may be used for the lipoprotein uptake assays, including high-throughput assays. The disclosed compositions and method may further be used to characterize the activity agents that inhibit or stimulate lipoprotein uptake.
REFERENCES:
Bernini et al. Arteriosclerosis, Thrombosis, and Vascular Biology. 1995;15(9):1352-1358.
Esbach et al. Hepathology 1993;18(3):537-545.
Adie et al. BioTechniques 2002;33:1152-1157.
CypHer Manual, Amersham, 2003.
Trigatti B, et al., “Influence of the High Density Lipoprotein Receptor SR-BI on Reproductive and Cardiovascular Pathophysiology,”Proc. Natl. Acad. Sci. U.S.A., 96, 9322-7 (1999).
Suzuki H., et al., “A Role for Macrophage Scavenger Receptors in Atherosclerosis and Susceptibility to Infection,”Nature, 386, 292-296 (1997).
Takahashi K., et al., “Multifunctional Roles of Macrophages in the Development and Progression of Atherosclerosis in Humans and Experimental Animals,”Med. Electron Microsc., 35, 179-203 (2002).
Linsel-Nitschke P., et al., “HDL as a Target in the Treatment of Atherosclerotic Cardiovascular Disease,”Nat. Rev. Drug Discov., 4, 193-205 (2005).
Lysco P., et al., “Identification of a Small-Molecule, Nonpeptide Macrophage Scavenger Receptor Antagonist,”J. Pharmacol Exp. Ther., 289, 1277-85 (1999).
Chow C.W., et al., “Measurement of Phagocytosis and Phagosomal Maturation,” p. 15.7.1-15.7.33 in J.S. Bonifacino et al. (Eds.),Current Protocols in Cell Biology, John Wiley & Sons, Inc. (2004).
Zhang J.H., et al., “A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays,”J. Biomol. Screen, 4, 67-73 (1999).
Beletskii Anton
Castle Jason William
Yu Liming
Bresnahan Maureen A.
General Electric Company
Gitomer Ralph
Shen Bin
Testa Jean K.
LandOfFree
Compositions and methods for lipoprotein uptake assays does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Compositions and methods for lipoprotein uptake assays, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions and methods for lipoprotein uptake assays will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3895703