Compositions and methods for labeling oligonucleotides

Details Compositions and methods for labeling oligonucleotides Compositions and methods for labeling oligonucleotides

2007-02-27

2007-02-27

Qian, Celine (Department: 1636)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

Reexamination Certificate

active

09894423

ABSTRACT:
A novel method for the labeling of oligonucleotides which results in the economical synthesis of 5′ labeled molecules. A set of suitably protected and carefully selected set of amino linkers, a modified deprotination/cleavage protocol and standard coupling methodologies to are used to allow for the convergent synthesis of any number of labeled oligonucleotides.

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