Drug – bio-affecting and body treating compositions – Dentifrices – Fluorine or fluorine compound containing
Patent
1977-12-29
1979-07-17
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Dentifrices
Fluorine or fluorine compound containing
424 54, A61K 718, A61K 722
Patent
active
041615182
ABSTRACT:
A dentifrice composition is provided containing a quaternary ammonium organosiloxane having the formula ##STR1## wherein R.sup.1 is an alkoxy group having from 1 to 5 carbon atoms, R.sup.2 is an alkylene group having from 1 to 25 carbon atoms, and R.sup.3, R.sup.4 and R.sup.5 are, individually, alkyl groups of from 1 to 25 carbon atoms, and X is an anion, preferably selected from chlorine, bromine fluorine and iodine. A method of inhibiting plaque formation on teeth in an oral environment is also provided.
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Iler Chem. Abstracts 50:5313c (1956) of U.S. Pat. No. 2,721,812; Oct. 25, 1955; "Quaternary Ammonium Organo Siloxanolates and their Applications," (Dispersing and Emulsifying Agents Showing Marked Surface Activity).
Morehouse Chem. Abstracts 55:13315c (1961) of U.S. Pat. No. 2,972,598, Feb. 21, 1961.
A.D.A. Accepted Dental Therapeutics 35th Ed. (1973), pp. 55:Silicone Fluids, 60-64 Quat. Amm. Cpds.; 193-194 Quat. Amm. Cpds.; 253-258:Dentrifrices and Mouthwashes; 264.gtoreq.266, Detergents-Surface Active Agents.
Engel Michael R.
LaFleur Linda L.
Lucas Anthony J.
Wen Richard Y.
Alexander C.
Lilly J. V.
Minnesota Mining and Manufacturing Company
Rose Shep K.
Sell D. M.
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