Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2011-02-15
2011-02-15
Anderson, Rebecca L (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S255010, C514S357000, C514S423000, C514S510000, C514S623000, C544S106000, C544S380000, C546S285000, C548S528000, C560S302000, C564S123000
Reexamination Certificate
active
07888355
ABSTRACT:
There are provided methods of inhibiting growth and metastasis of melanoma, methods of sensitizing melanoma cells to apoptosis, and methods of treating a subject having melanoma using acetyl isogambogic acid, celastrol, or a derivative thereof. There are further provided derivatives of celastrol and compositions comprising acetyl isogambogic acid, celastrol, or a derivative thereof.
REFERENCES:
Nagase et al. Biosci. Biotechnol. Biochem. (2003) 67 (9) pp. 1883-1887.
Bhoumik Anindita
Cosford Nicholas D. P.
Dahl Russell
Ronai Ze′ev A.
Anderson Rebecca L
Burnham Institute for Medical Research
DLA Piper (LLP) US
Shterengarts Samantha L
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