Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1992-07-27
1995-05-30
Schain, Howard E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
530324, 435218, A61K 3843, A61K 3855
Patent
active
054201101
ABSTRACT:
This invention provides a compound comprising:
REFERENCES:
patent: 4485100 (1984-01-01), Hochstrasser et al.
patent: 4496689 (1985-01-01), Mitra
Satoh et al, The Dual Nature of the Reaction Between Porciene Elastase and Human Plasma .alpha., Prdenare Inhibitor vol. 86, No. 1, 1979. Biochem Biophys Res.
Lo et al. The Interaction of .alpha.-1-Antitrupsin with Soluble and Sepharnose Sound Elastase. Biochem & Biophys Acta 453 (1976), 344-346.
Perlmutter, et al., "Identification of a serpin-enzyme complex receptor on human hepatoma cells and human monocytes," Proc. Natl. Acad. Sci. USA 87:3753-3757 (1990).
Kress et al., "Characterization of the Inactive Fragment Resulting from Limited Proteolysis of Human .alpha..sub.1 -Proteinase Inhibitor by Crotalus adamanteus Proteinase II", The Journal of Biological Chemistry, 254:5317-53200 (1979).
Michaelis, et al., "Human neutrophil collagenase cleaves .alpha..sub.1 -antitrypsin", Biochem. J. 270:809-814 (1990).
Carrell et al., "Serpins: the superfamily of plasma serine proteinase inhibitors," in Proteinase Inhibitors (Barrett and Salvesen, eds.), Chapter 12, pp. 403-420.
Schain Howard E.
Touzeau L.
UAB Research Foundation
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