Compositions and methods for increasing bone mineralization

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C536S023200, C435S320100, C435S252300, C435S254110, C435S325000, C435S419000, C435S069100

Reexamination Certificate

active

07994299

ABSTRACT:
A novel class or family of TGF-β binding proteins is disclosed. Also disclosed are assays for selecting molecules for increasing bone mineralization and methods for utilizing such molecules.

REFERENCES:
patent: 4331647 (1982-05-01), Goldenberg
patent: 4376110 (1983-03-01), David et al.
patent: 4411993 (1983-10-01), Gillis
patent: 4427115 (1984-01-01), Laipply
patent: 4543439 (1985-09-01), Frackelton, Jr. et al.
patent: RE32011 (1985-10-01), Zimmerman et al.
patent: 4837440 (1989-06-01), Burtscher et al.
patent: 4902614 (1990-02-01), Wakabayashi et al.
patent: 5070108 (1991-12-01), Margolis
patent: 5145684 (1992-09-01), Liversidge et al.
patent: 5223409 (1993-06-01), Ladner et al.
patent: 5399363 (1995-03-01), Liversidge et al.
patent: 5453492 (1995-09-01), Butzow et al.
patent: 5466468 (1995-11-01), Schneider et al.
patent: 5543158 (1996-08-01), Gref et al.
patent: 5552157 (1996-09-01), Yagi et al.
patent: 5565213 (1996-10-01), Nakamori et al.
patent: 5567434 (1996-10-01), Szoka, Jr.
patent: 5627052 (1997-05-01), Schrader et al.
patent: 5641515 (1997-06-01), Ramtoola et al.
patent: 5698426 (1997-12-01), Huse
patent: 5738868 (1998-04-01), Shinkarenko et al.
patent: 5780263 (1998-07-01), Hastings et al.
patent: 5795587 (1998-08-01), Gao et al.
patent: 5811238 (1998-09-01), Stemmer et al.
patent: 5830721 (1998-11-01), Stemmer et al.
patent: 5837458 (1998-11-01), Minshull et al.
patent: 5877397 (1999-03-01), Lonberg et al.
patent: 6054561 (2000-04-01), Ring
patent: 6057421 (2000-05-01), Muller et al.
patent: 6117911 (2000-09-01), Grainger et al.
patent: 6133426 (2000-10-01), Gonzalez et al.
patent: 6180370 (2001-01-01), Queen et al.
patent: 6207153 (2001-03-01), Dan et al.
patent: 6395511 (2002-05-01), Brunkow et al.
patent: 6489445 (2002-12-01), Brunkow et al.
patent: 6495736 (2002-12-01), Brunkow et al.
patent: 6703199 (2004-03-01), Koide
patent: 6803453 (2004-10-01), Brunkow et al.
patent: 6806055 (2004-10-01), Berman et al.
patent: 6815201 (2004-11-01), Pinter
patent: 6818748 (2004-11-01), Fulton et al.
patent: 7192583 (2007-03-01), Brunkow et al.
patent: 7572899 (2009-08-01), Brunkow et al.
patent: 2003/0165410 (2003-09-01), Taylor
patent: 2003/0186915 (2003-10-01), Pan et al.
patent: 2004/0009535 (2004-01-01), Brunkow et al.
patent: 2004/0023356 (2004-02-01), Krumlauf et al.
patent: 2004/0058321 (2004-03-01), Brunkow et al.
patent: 2004/0141875 (2004-07-01), Doshi
patent: 2004/0146888 (2004-07-01), Paszty et al.
patent: 2004/0158045 (2004-08-01), Brunkow et al.
patent: 2005/0106683 (2005-05-01), Winkler et al.
patent: 2005/0238646 (2005-10-01), Ledbetter et al.
patent: 2006/0233801 (2006-10-01), Brunkow et al.
patent: 2007/0110747 (2007-05-01), Paszty et al.
patent: 2007/0292444 (2007-12-01), Krumlauf et al.
patent: 102 55 152 (2004-06-01), None
patent: 2 838 379 (2003-10-01), None
patent: 4-141095 (1992-05-01), None
patent: WO-91/13152 (1991-09-01), None
patent: WO-92/02551 (1992-02-01), None
patent: WO-92/06693 (1992-04-01), None
patent: WO-95/30003 (1995-11-01), None
patent: WO-98/21335 (1998-05-01), None
patent: WO-99/03996 (1999-01-01), None
patent: WO-99/06554 (1999-02-01), None
patent: WO-99/15556 (1999-04-01), None
patent: WO-00/32773 (2000-06-01), None
patent: WO-00/75317 (2000-12-01), None
patent: WO-01/64885 (2001-09-01), None
patent: WO-01/92308 (2001-12-01), None
patent: WO-01/98491 (2001-12-01), None
patent: WO-02/24888 (2002-03-01), None
patent: WO-03/106657 (2003-12-01), None
patent: WO-2005/003158 (2005-01-01), None
patent: WO-2005/014650 (2005-02-01), None
Alting-Mees et al., “Monoclonal Antibody Expression Libraries: A Rapid Alternative to Hybridomas,”Strategies in Molecular Biology, 3:1-9 (1990).
Alves et al., “Sclerosteosis: A Marker of Dutch Ancestry?”Rev. Bras. Genet., 4:825-834 (1982).
Angal et al., “A Single Amino Acid Substitution Abolishes the Heterogeneity of Chimeric Mouse/Human (IgG4) Antibody,”Mol. Immunol., 30(1):105-108 (1993).
Avsian-Kretcher et al., “Comparative Genomic Analysis of the Eight-Membered Ring Cystine Knot-Containing Bone Morphogenetic Protein Antagonists,”Mol. Endo., 18(10:1-12 (2004).
Babcook et al., “A Novel Strategy for Generating Monoclonal Antibodies from Single, Isolated Lymphocytes Producing Antibodies of Defined Specificities,”Proc. Natl. Acad. Sci.(USA), 93:7843-7848 (1996).
Baines et al., “Purification of Immunoglobulin G (IgG),” Methods in Molecular Biology, 10:79-104, The Humana Press, Inc. (1992).
Balemans et al., “Extracellular Regulation of BMP Signaling in Vertebrates: A Cocktail of Modulators,”Dev. Biol., 250:231-250 (2002).
Balemans et al., “Increased Bone Density in Sclerosteosis is due to the Deficiency of a Novel Secreted Protein (SOST),”Hum. Mol. Genet., 10:537-543 (2001).
Beighton et al., “The Clinical Features of Sclerosteosis,”Annals of Internal Medicine, 84:393-397 (1976).
Beighton et al., “The Syndromic Status of Sclerosteosis and van Buchem Disease,”Clinical Genetics, 25:175-181 (1984).
Bendayan, M., “Possibilities of False Immunocytochemical Results Generated by the Use of Monoclonal Antibodies: The Example of the Anti-proinsulin Antibody,”Histochemistry and Cytochemistry43(9):881-886 (1995).
Berman et al., “The Protein Data Bank,”Acta. Cryst., 58(10:899-907 (2002).
Bird et al., “Single-Chain Antigen-Binding Proteins,”Science, 242:423-426 (1988).
Birren et al., Accession No. AC003098,EMBL Sequence Database(1997).
Birren et al., “Homo sapienschromosome 17, clone RP5-905N1,”EMBL Sequence Database, AC003098.2 (2006).
Black et al., “A Somatic Cell Hybrid Map of the Long Arm of Human Chromosome 17, Containing the Familial Breast Cancer Locus (BRCAI),”Am. J. Hum. Genet., 52:702-710 (1993).
Boden et al., “Glucocorticoid-Induced Differentiation of Fetal Rat Calvarial Osteoblasts is Mediated by Bone Morphogenetic Protein-6,”Endocrinology, 138(7):2820-2828 (1997).
Boerner et al., “Production of Antigen-Specific Human Monoclonal Antibodies from in Vitro-Primed Human Splenocytes,”J. Immunol., 147:86-95 (1991).
Bonaldo et al., “Accession No. AI113131,”EMBL Sequence Database(1998).
Bonaldo et al., “Normalization and Subtraction: Two Approaches to Facilitate Gene Discover,”Genome Res., 6(9):791-806 (1996).
Bondestam, “Ligands & Signaling Components of the Transforming Growth Factor,” Helsinki University Biomedical Dissertations (2002).
Bost et al., “Antibodies Against a Peptide Sequence Within the HIV Envelope Protein Crossreacts with Human Interleukin-2,”Immunological Investigations, 17(6&7):577-586.
Bostrom et al., “Ligand & Signaling Components of teh Transforming Growth Factor β Family,”J. Orth. Res., 13:357-367 (1995).
Bowie et al., “A Method to Identify Protein Sequences taht Fold into a Known Three-Dimensional Structure,”Science, 253:164-170 (1991).
Bowie et al., “Deciphering the Message in Protein Sequences: Tolerance to Amino Acid Substitutions,”Science247:1306-1310 (1990).
Bradley et al., “Modifying the Mouse: Design and Desire,”Bio/Technology, 10:534-539 (1992).
Brenner et al., Curr. Op. Struct. Biol., 7(3):369-376 (1997).
Brown, T., “Hybridization Analysis of DNA Blots,” 2.10.1-2.10.16 (2000).
Bruggemann et al., “Production of Human Antibody Repertoires in Transgenic Mice,”Curr. Opin. Biotechnol., 8:455-458 (1997).
Brunkow et al., “Bone Dysplasia Sclerosteosis Results from Loss of the SOST Gene Product, a Novel Cysteine Knot-Containing Protein,”Am. J. Hum. Genet., 68:577-589 (2001).
Burton et al., “Human Antibodies from Combinatorial Libraries,”Adv. Immunol., 57:191-280 (1994).
Byrne et al., “CD4+CD45RBHi T Cell Transfer Induced Colitis in Mice is Accompanied by Osteopenia which is Treatable with Recombinant Human Osteoprotegerin,”Gut, 54:78-86 (2005).
Campbell e

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Compositions and methods for increasing bone mineralization does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compositions and methods for increasing bone mineralization, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions and methods for increasing bone mineralization will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2738794

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.