Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2005-01-18
2005-01-18
Helms, Larry R. (Department: 1642)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C436S064000
Reexamination Certificate
active
06844153
ABSTRACT:
Screening and diagnostic reagents, kits and methods for metastatic colorectal cancer or primary and/or metastatic stomach or esophageal cancer are disclosed. Vaccines compositions and methods of for treating and preventing metastatic colorectal cancer or primary and/or metastatic stomach or esophageal cancer are disclosed.
REFERENCES:
patent: 5601990 (1997-02-01), Waldman
patent: 5879656 (1999-03-01), Waldman
patent: 6130043 (2000-10-01), Billing-Medel et al.
patent: WO 0020640 (2000-04-01), None
Bai et al (Cancer Lett 2002 Feb. 8;176(1):47-55, abstract only).*
Mallo, et al., Int J Cancer, 1997, 74:35-44.*
Iannettoni, M.D. et al., “Detection of Barrett's aenocarcinoma of the gastric cardia with sucrase isomaltase and p53”,Ann. Thorac. Surg., 1996, 62, 1460-1466.
Mallo, G.V., et al., “Molecular cloning, sequencing and expression of the MRNA encloding human Cdx1 and Cdx2 homeobox. Down-regulation of Cdx1 and Cdx2 mRNA expression during colorectal carcinogenesis,”Int. J. Cancer(Pred. Oncol), 1997, 74, 35-44.
Wu, G.D., et al., “Sucrase-isomaltase gene expression in barrett's esophagus and adenocarcinoma,”Gastroenterology, 1993, 105, 837-844.
Cagir, B., et al., “Guanylyl cyclase C messenger RNA is a biomarker for recurrent stage II colorectal cancer,”Am. Soc. Internal Med., 1999, 131(11), 805-812.
Li,Z., et al., “Peptide-regulated guanylate cyclase pathways in rat colon: in situ localization of GCA, GCC, and guanylin mRNA,”Am. Physiological Soc., 1993, G394-G402.
London, R.M., et al., “Signal transduction pathways via guanylin uroguanylin in stomach and intestine,”Am. Physiological Soc., 1997, G93-G105.
Mallo, G.V., et al., “Expression of theCdx1andCdx2homeotic genes leads to reduced malignancy in colon cancer-derived cells,”J. Biological Chem., 1998, 273(22), 14030-14036.
Park Jason
Schulz Stephanie
Waldman Scott A.
Helms Larry R.
O'Connor P.C. Cozen
Thomas Jefferson University
Yu Misook
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