Drug – bio-affecting and body treating compositions – Nonspecific immunoeffector – per se ; or nonspecific... – Synthetic polymer or copolymer
Patent
1996-08-20
1998-10-20
Achutamurthy, Ponnathapura
Drug, bio-affecting and body treating compositions
Nonspecific immunoeffector, per se ; or nonspecific...
Synthetic polymer or copolymer
4242781, 4242831, 4242791, 568624, 514723, 5147723, A61K 4500, A61K 4732, A01N 3114
Patent
active
058243224
ABSTRACT:
The present invention includes compositions and methods using biologically active nonionic reverse block copolymers. The reverse copolymers have an inner core of polyoxypropylene (POP) that is flanked on either end by polyoxyethylene (POE). The reverse block copolymers have the following formula: ##STR1## wherein "b" represents a number such that the molecular weight of the hydrophobe (C.sub.3 H.sub.6 O).sub.b is between approximately 2,000 and 10,000, and "a" represents a number such that the percentage of hydrophile (C.sub.2 H.sub.4 O).sub.a is between approximately 5% and 30%. The reverse block copolymers stimulate the immune response, can suppress immune responses such as those in autoimmune diseases, promote the growth of animals, and stimulate hormone production.
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Achutamurthy Ponnathapura
Cytrx Corporation
Ponnaluri P.
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