Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus
Reexamination Certificate
2003-06-03
2009-02-03
Marvich, Maria B (Department: 1633)
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Genetically modified micro-organism, cell, or virus
C435S320100, C435S069100, C435S325000, C435S326000, C536S024100
Reexamination Certificate
active
07485291
ABSTRACT:
Single vector constructs for expression of a functional antibody molecule are described. The vectors have a self-processing cleavage site between two heterologous DNA coding sequences allowing for expression of two coding sequences using a single promoter. Exemplary vector constructs comprise a foot and mouth disease virus (FMDV) 2A sequence. The vector constructs can be used in methods relating to antibody delivery and therapy and in the production of a biologically active antibody or fragment thereof.
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Borm
Fang Jianmin
Jooss Karin
Qian Jing-Jing
Cell Genesys Inc.
Chen Teresa
Haley Jr. James F.
Marvich Maria B
Ropes & Gray LLP
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