Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2004-08-03
2008-09-30
Blanchard, David J. (Department: 1643)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C435S005000, C435S069100, C435S069700, C435S235100, C435S320100, C435S328000, C530S387300, C424S133100
Reexamination Certificate
active
07429652
ABSTRACT:
The present invention provides a technique for specific assembly of monomeric polypeptides to form a heteromultimer. This technique is particularly useful for generating a genetically diverse repertoire of heteromultimers such as antigen-binding units. The invention also provides both non-single-chain and single-chain antigen-binding units that are assembled by the technique described herein. The present invention also provides recombinant polynucleotides, vectors, host cells, and kits for producing the subject antigen-binding units. Further provided by the invention are methods of using the subject antigen-binding units.
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De Kruif and Log
Li Shengfeng
Liu Shengjiang
Luo Peizhi
Wang Caili
Wang Xinwei
Abmaxis, Inc.
Blanchard David J.
Chisholm Patricia L.
Krovatin William
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