Drug – bio-affecting and body treating compositions – Lymphokine
Patent
1991-12-10
1992-10-06
Nucker, Christine M.
Drug, bio-affecting and body treating compositions
Lymphokine
424 88, 4352351, A61K 3912, A61K 3900, C12N 700
Patent
active
051529823
ABSTRACT:
Novel methods and compositions are provided for vaccinating a host susceptible to viral infection. Particularly, an initial injection is employed of one or more polypeptides associated with the host immune response to the pathogen followed by administration of the pathogen in attenuated form, particularly having a deletion associated with the gene expressing at least one of said polypeptides. In this manner, hosts may be vaccinated so as to maintain a strong defensive posture against infection from the pathogen. The method is specifically illustrated with feline leukemia virus.
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Dina Dino
Luciw Paul
Parkes Deborah
Van Nest Gary
Chiron Corporation
Nucker Christine M.
Smith Lynette F.
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