Compositions and methods for enhancing wound healing

Details Compositions and methods for enhancing wound healing Compositions and methods for enhancing wound healing

1993-11-29

1995-10-24

Schain, Howard E.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

514 3, 514 12, A61K 3174, A61K 3800, C12N 500, C12N 502

Patent

active

054610303

ABSTRACT:
The present invention relates to formulations and methods for treating wounds utilizing these formulations. The formulations according to the present invention are useful for treating wounds by accelerating wound healing. These formulations comprise an effective amount of a serum free cellular nutrient medium in combination with an effective amount of at least one cellular growth stimulating compound, e.g. a natural anabolic hormone or transforming growth factor.

REFERENCES:
patent: 3664925 (1972-05-01), Sonenberg et al.
patent: 3904753 (1975-09-01), Sonenberg et al.
patent: 4444760 (1984-04-01), Thomas, Jr.
patent: 4503037 (1985-03-01), Szijjarto et al.
patent: 4658021 (1987-04-01), Goeddel et al.
patent: 4673649 (1987-06-01), Boyce et al.
patent: 4696917 (1987-09-01), Lindstrom et al.
patent: 4863899 (1989-09-01), Todaro
patent: 4886786 (1989-12-01), Lindstrom et al.
patent: 4940666 (1990-07-01), Boyce et al.
patent: 5013714 (1991-05-01), Lindstrom et al.
patent: 5034375 (1991-07-01), Antoniades et al.
patent: 5035887 (1991-07-01), Antoniades et al.
patent: 5051443 (1991-09-01), Neufeld et al.
patent: 5056520 (1977-11-01), Sonenberg et al.
patent: 5165938 (1992-11-01), Knighton
patent: 5204325 (1993-04-01), Lindstrom et al.
patent: 5218093 (1993-06-01), Guo et al.
patent: 5219739 (1993-06-01), Tischer et al.
Lynch et al Proc. Nat'l Acad Science USA 84 1987 pp. 7696-7700.
Diane Krasner, ed. Chronic Wound Care: A Clinical Source Book for Health Care Professionals pp. 311-317.
Hayward et al., "Animal Models of Wound Contraction", Clinical and Experimental Approaches to Dermal . . . ,301-312, 1991, Wiley-Liss, Inc.
Mulder, "If Wounds Could Talk", Clinical and Experimental Approaches to Dermal and Epidermal Repair: Normal and Chronic Wounds, 55-66, 1991, Wiley-Liss, Inc.
Liss, Culture of Animal Cells, 238-241, 1988, Alan R. Liss, Inc. New York.
Barnes, et al., "Serum-Free Cell Culture: A Unifying Approach", Cell, vol. 22, 649, 1980.
Ham, "Growth of Normal Human Cells in Defined Media", 16-30.
Tsao et al., "Clonal Growth of Normal Human Epidermal Keratinocytes in a Defined Medium", Journal of Cellular Physiology, 110, 219, 1982.
Wille et al., "Integrated Control of Growth and Differentiation of Normal Human . . . " Journal of Cellular Physiology, 121, 31, 1984.
Boyce et al., "Calcium-Regulated Differentiation of Normal Human Epidermal Keratinocytes . . . " Journal of Investigative Dermatology, 81, 335, 1983.
Pierce et al. "Platelet-derived Growth Factor and Transforming Growth Factor-.beta. Enhance Tissue Repair Activities by Unique Mechanisms", J. Cell Bio., Jul. '89.
Lynch et al. "Role of platelet-derived growth factor in wound healing: Synergistic effects with other growth factors," Proc. Natl. Acad. Sci. USA, vol. 84, pp. 7696-7700, Nov. '87.

Affiliated with

Also associated with

Rating

Compositions and methods for enhancing wound healing does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compositions and methods for enhancing wound healing, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions and methods for enhancing wound healing will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1886639