Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2011-01-18
2011-01-18
Babic, Christopher M. (Department: 1637)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
Reexamination Certificate
active
07871776
ABSTRACT:
A method for purifying PrPc, a purified preparation of PrPcand methods and kits for identifying the presence of PrPcare provided.
REFERENCES:
patent: 6239157 (2001-05-01), Mbalaviele
patent: 6406907 (2002-06-01), Taylor et al.
patent: 6670328 (2003-12-01), Lassalle et al.
patent: 7407760 (2008-08-01), Supattapone et al.
patent: 2002/0001817 (2002-01-01), Prusiner et al.
patent: 2002/0137114 (2002-09-01), Voelkel et al.
Saborio et al. (Biochem Biophys Res Commun. May 10, 1999;258(2):470-5).
Stratagene (“Gene Characterization Kits” 1988).
Ahmad et al. (Thromb Res. Jul. 1, 1989;55(1):121-33).
Bessen et al., “Non-genetic propagation of strain-specific properties of scrapie prior protein”, Nature 1995 375:698-700.
Brimacombe et al., “Characterization and polyanion-binding properties of purified recombinant prior protein”, Biochem. J. 1999 342:605-613.
Brown et al., “Consequences of manganese replacement of copper for prion protein function and proteinase resistance”, The EMBO Journal 2000 19(6):1180-1186.
Caughey, B., “Formation of Protease-Resistant Prion Protein in Cell-Free Systems”, Curr. Issues Mol. Biol. 2000 2(3):95-101.
Cordeiro et al., “DNA Converts Cellular Prion Protein into the β-Sheet Conformation and Inhibits Prion Peptide Aggregation”, J. Biol. Chem. 2001 276(52):49400-49409.
Derrington et al., “PrPchas nucleic acid chaperoning properties similar to the nucleocapsid protein of HIV-1”, C.R. Biologies 2002 325:17-23.
Gabus et al., “The Prion Protein Has RNA Binding and Chaperoning Properties Characteristic of Nucleocapsid Protein NCp7 of HIV-1”, J. Biol. Chem. 2001 276(22):19301-19309.
Gabus et al., “The Prion Protein has DNA Strand Transfer Properties Similar to Retroviral Nucleocapsid Protein”, J. Mol. Biol. 2001 307:1011-1021.
Horiuchi et al., “Specific binding of normal prion protein to the scrapie form via a localized domain initiates its conversion to the protease-resistant state” The EMBO Journal 1999 18(12):3193-3203.
Horiuchi et al., “Prion protein interconversions and the transmissible spongiform encephalopathies”, Structure 1999 7(10):R231-R240.
Kocisko et al., “Species specificity in the cell-free conversion of prion protein to protease-resistant forms:A model for the scrapie species barrier”, Proc. Natl. Acad. Sci. USA 1995 92:3923-3927.
Kocisko et al., “Cell-free formation of protease-resistant prion protein”, Nature 1994 370:471-474.
Moscardini et al., “Functional Interactions of Nucleocapsid Protein of Feline Immunodeficiency Virus and Cellular Prion Protein with the Viral RNA”, J. Mol. Biol. 2002 318:149-159.
Nandi et al., “DNA-induced Partial Unfolding of Prion Protein Leads to its Polymerisation to Amyloid”, J. Mol. Biol. 2002 322:153-161.
Nandi et al., “Unusual Property of Prion Protein Unfolding in Neutral Salt Solution”, Biochemistry 2002 41:11017-11024.
Proske et al., “Prion-Protein-Specific Aptamer Reduces PrPScFormation”, ChemBioChem 2002 3:717-725.
Saborío et al., “Cell-Lysate Conversion of Prion Protein into Its Protease-Resistant Isoform Suggests the Participation of a Cellular Chaperone”, Biochemical and Biophysical Research Communications 1999 258:470-475.
Warner et al., “Identification of the Heparan Sulfate Binding Sites in the Cellular Prion Protein”, J. Biol. Chem. 2002 277(21):18421-18430.
Weiss et al., “RNA Aptamers Specifically Interact with the Prion Protein PrP”, Journal of Virology 1997 71(11):8790-8797.
Zeiler et al., “Concentration and removal of prion proteins from biological solutions”, Biotechnol. Appl. Biochem. 2003 37:137-182.
Pan et al., “Conversion of α-helices into β-sheets featuresin the formation of the scrapie prion proteins”, Proc. Natl. Acad. Sci. USA 1993 90:10962-10966.
Saborio et al. (“Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding” Nature. Jun. 14, 2001;411(6839):810-3).
Saborio at al. (“Cell-lysate conversion of prion protein into its protease-resistant isoform suggests the participation of a cellular chaperone” Biochem Biophys Res Commun. May 10, 1999;258(2):470-5).
Deleault Nathan
Supattapone Surachai
Babic Christopher M.
Licata & Tyrrell P.C.
Trustees of Dartmouth College
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