Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...
Reexamination Certificate
2006-08-29
2006-08-29
Ketter, James (Department: 1636)
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Introduction of a polynucleotide molecule into or...
C424S450000, C536S023100
Reexamination Certificate
active
07098032
ABSTRACT:
An polyampholyte is utilized in a condensed polynucleotide complex for purposes of nucleic acid delivery to a cell. The complex can be formed with an appropriate amount of positive and/or negative charge such that the resulting complex can be delivered to the extravascular space and may be further delivered to a cell.
REFERENCES:
patent: 6881516 (2005-04-01), Aamodt et al.
patent: 2005/0170505 (2005-08-01), Wakefield et al.
Budker Vladimir G.
Hagstrom James E.
Monahan Sean D.
Rozema David B.
Trubetskoy Vladimir S.
Ekana Kirk
Johnson Mark K.
Ketter James
Mirus Bio Corporation
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