Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1995-05-24
1997-11-11
Hutzell, Paula K.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
436518, 436519, 436161, 436174, 436811, G01N 3353
Patent
active
056862555
ABSTRACT:
Methods and compositions for detecting schizophrenia based on modification of the dopamine D.sub.4 receptor by addition of an adenosyl group to methionine #313 via methionine adenosyltransferase are described herein. Individuals with schizophrenia have a deficiency in methionine adenosyltransferase activity and a lower amount of modified dopamine D.sub.4 receptor than normal individuals. Methods for screening therapeutic processes, agents and drugs for use in treatment of schizophrenia are also described.
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Duffy Patricia A.
Hutzell Paula K.
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