Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2006-03-06
2008-08-05
Minnifield, N. M. (Department: 1645)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S069100, C435S366000, C424S184100, C424S234100
Reexamination Certificate
active
07407770
ABSTRACT:
The invention provides compositions and methods for the detection and quantification ofEhrlichia chaffeensisorEhrlichia canis, Ehrlichia chaffeensisorEhrlichia canisantibodies, antibody fragments, and polypeptides.
REFERENCES:
patent: 4275149 (1981-06-01), Litman et al.
patent: 4318980 (1982-03-01), Boguslaski et al.
patent: 4676980 (1987-06-01), Segal et al.
patent: 5192679 (1993-03-01), Dawson et al.
patent: 5401656 (1995-03-01), Dawson
patent: 5413931 (1995-05-01), Dawson et al.
patent: 5726010 (1998-03-01), Clark
patent: 5789176 (1998-08-01), Dawson et al.
patent: 5869335 (1999-02-01), Munderloh et al.
patent: 5928879 (1999-07-01), Dumler et al.
patent: 5955359 (1999-09-01), Dumler et al.
patent: 5976791 (1999-11-01), Mabilat et al.
patent: 5976860 (1999-11-01), Coughlin et al.
patent: 5989848 (1999-11-01), Dawson
patent: 6015691 (2000-01-01), Walker et al.
patent: 6025338 (2000-02-01), Barbet et al.
patent: 6034085 (2000-03-01), Joshl et al.
patent: 6204252 (2001-03-01), Murphy et al.
patent: 6207169 (2001-03-01), Reed et al.
patent: 6231869 (2001-05-01), Reed et al.
patent: 6251872 (2001-06-01), Barbet et al.
patent: 6277381 (2001-08-01), Reed et al.
patent: 6284238 (2001-09-01), Coughlin et al.
patent: 6306394 (2001-10-01), Murphy et al.
patent: 6306402 (2001-10-01), Reed et al.
patent: 6355777 (2002-03-01), Walker et al.
patent: 6392023 (2002-05-01), Walker et al.
patent: 6403780 (2002-06-01), Walker et al.
patent: 6458942 (2002-10-01), Walker et al.
patent: 6593147 (2003-07-01), Barbet et al.
patent: 2002/0064531 (2002-05-01), Walker et al.
patent: 2002/0064535 (2002-05-01), Reed et al.
patent: 2002/0068343 (2002-06-01), Reed et al.
patent: 2002/0086984 (2002-07-01), Reed et al.
patent: 2002/0115840 (2002-08-01), Walker et al.
patent: 2002/0120115 (2002-08-01), Rikihisa et al.
patent: 2002/0132789 (2002-09-01), Barbet et al.
patent: 2002/0160432 (2002-10-01), Lawton et al.
patent: 2002/0177178 (2002-11-01), Lawton et al.
patent: 2003/0119082 (2003-06-01), Lawton et al.
patent: 2003/0129680 (2003-07-01), O'Connor
patent: 2003/0194756 (2003-10-01), O'Connor
patent: 2003/0194757 (2003-10-01), O'Connor et al.
patent: 2005/0124015 (2005-06-01), O'Connor et al.
patent: 2006/0189537 (2006-08-01), O'Connor
patent: 2007/0020733 (2007-01-01), Lawton
patent: 2007/0026474 (2007-02-01), Lawton
patent: WO 99/13720 (1999-03-01), None
patent: WO99/13720 (1999-03-01), None
patent: WO 00/65064 (2000-11-01), None
patent: WO 01/85949 (2001-11-01), None
patent: 02/01395 (2002-01-01), None
patent: WO 02/057794 (2002-07-01), None
patent: 03/10131 (2003-04-01), None
patent: WO 2006/138509 (2006-12-01), None
Greenspan et al. (Nature Biotechnology 7: 936-937, 1999).
Bowie et al (Science, 1990, 257:1306-1310).
McGuinnes et al. (Mol. Microbiol. 7: 505-514, Feb. 1993).
McGuinnes et al. (Lancet 337: 514-517, Mar. 1991).
Waner et al (J Vet Diagn Invest, 2000, 12:240-244).
Cadman et al (Veterinary Record, 1994, 135, 362).
Ohashi, et al., “Immunodominant Major Outer Membrane Proteins ofEhrlichia chaffeensisare Encoded by a Polymorphic Multigene Family”,Infection and Immunity, 66, p. 132-139 (1998).
Ohashi, et al., “Cloning and Characterization of Multigenes Encoding the Immunodominant 30-Kilodalton Major Outer Membrane Proteins ofEhrlichia canisand Application of the Recombinant Protein for Serodiagnosis”,Journal of Clinical Microbiology, 36, p. 2371-2680 (1998).
Yu, et al., “Genetic Diversity of the 28-Kilodalton Outer Membrane Protein Gene in Human Isolates ofEhrlichia chaffeensis”, Journal of Clinical Microbiology, 37, p. 1137-1143 (1999).
McBride, et al., “Molecular Cloning of the Gene for a Conserved Major Immunoreactive 28-Kilodalton Protein ofEhrlichia canis: a Potential Serodiagnostic Antigen”,Clinical and Diagnostic Laboratory Immunology, 6, p. 392-399 (1999).
Yu, et al., “Comparison ofEhrlichia chaffeensisRecombinant Proteins for Serologic Diagnosis of Human MonocytotropicEhrlichiosis”, Journal of Clinical Microbiology, 37, p. 2568-2575 (1999).
Yu, et al., “Characterization of the Complete Transcriptionally ActiveEhrlichia chaffeensis28 kDa Outer Membrane Protein Multigene Family”,Gene, 248, p. 59-68 (2000).
McBride, et al., “A Conserved, Transcriptionally Action p28 Multigene Locus ofEhrlichia canis”, Gene254, p. 245-252 (2000).
Suksawat, et al., “Seroprevalence ofEhrlichia canis, Ehrlichia equi, andEhrlichia risticii, in Sick Dogs from North Carolina and Virginia”,Journal of Vet. Internal. Med., 14, p. 50-55 (2000).
Waner, et al., “Comparison of a clinic-based ELISA test kit with the immunofluorescence test for the assay ofEhrlichia canisantibodies in dogs”,J. Vet. Diagn. Invest., 12:240-244 (2000).
Cadman, et al., “Comparison of the dot-blot enzyme linked immunoassay with immunofluorescence for detecting antibodies toEhrlichia canis”, Veterinary Record, 135, 362 (1994).
Zhi, et al., “Cloning and expression of the 44-kilodalton major outer membrane protein gene of the human granulocytic ehrlichiosis agent and application of the recombinant protein to serodiagnosis”,Journal of Clinical Microbiology, p. 1666-1673 (1998).
Unver, et al., “Western and dot blotting analyses ofEhrlichia chaffeensisindirect fluorescent-antibody assay-positive and -negative sera by using native and recombinantE. chaffeensisandE. canisantigens”,Journal of Clinical Microbiology, p. 3888-3895 (1999).
McBride, et al., “Immunodiagnosis ofEhrlichia canisinfection with recombinant proteins”,Journal of Clinical Microbiology, p. 15-322 (2001).
Reddy, et al., “Molecular Characterization of a 28 kDa Surface Antigen Gene Family of the Tribe Ehrlichiae”,Biochemical and Biophysical Research Communications, 247, p. 636-643 (1998).
O'Connor et al., “Comparison of an indirect immunofluorescence assay, western blot analysis, and a commercially available ELISA for detection ofEhrlichia canisantibodies in canine sera”,AJVR. vol. 67, No. 2, p. 206-210 (2006).
U.S. Appl. No. 60/335,367, filed Oct. 31, 2001.
O'Connor, “Dogs Vaccinated with Common Lyme Disease Vaccines do not Respond to IR6, the Conserved Immunodominant Region of the VIsE Surface Protein ofBorrelia burgdorferi”, Clinical and Diagnostic Laboratory Immunology, May 2004, p. 458-462 (2004).
Harrus, et al., “Comparison of three enzyme-linked immunosorbant assays with the indirect immunofluorescent antibody test for the diagnosis of canine infection withEhrlichia canis”, Veterinary Microbiology, 86 (2002) 361-368.
Köhler, et al., “Continuous cultures of Fused Cells Secreting Antibody of Predefined Specificity”, Nature, vol. 256, pp. 495-497, 1975.
Bowie, et al., “Deciphering the Message in Protein Sequences: Tolerance to Amino Acid Substitutions”, Science, vol. 247, pp. 1306-1310, 1990.
Cunningham, et al., “High-Resolution Eptiope Mapping of hGH-Receptor Interactions by Alanine-Screening Mutagenesis”, Science, vol. 244, p. 1081-1085, 1989.
Wright, et al., “Genetically Engineered Antibodies: Progress and Prospects”, Critical Reviews in Immunology, 12(3,4):125-168, 1992.
Morrison, “In Vitro Antibodies: Strategies for Production and Application”, Annu. Rev. Immunol., 10:239-65, 1992.
Dean, “Preparation and Testing of Monoclonal Antibodies to Recombinant Proteins”, Methods in Molecular Biology, vol. 80, p. 23-37, 1994.
Dean, Preparation and characterization of Monoclonal Antibodies to Proteins and Other Cellular Components:, Methods in Molecular Biology, vol. 32, pp. 361-379, 1994.
Bailey, “The Raising of a Polyclonal Antiserum to a Protein”, Methods in Molecular Biology, vol. 32, pp. 381-388, 1994.
Gullick, “Production of Antisera to Synthetic Peptides”, Methods in Molecular Biology, vol. 32, pp. 389-399, 1994.
Tam, “Recent advances in multiple antigen peptides”, Journal of Immunological Methods 196 (1996) 17-32.
Ford Vanessa L.
IDEXX Corporation
McDonnell Boehnen & Hulbert & Berghoff LLP
Minnifield N. M.
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