Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2007-07-24
2007-07-24
Shukla, Ram R. (Department: 1634)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S091200, C435S253100, C536S023100, C536S024300
Reexamination Certificate
active
10216817
ABSTRACT:
The present invention pertains to polynucleotides derived fromM. tuberculosisgenes imparting resistance to antibiotics and chemically related compounds. This invention also relates to the use of the polynucleotides as oligonucleotide primers or probes for detectingM. tuberculosisstrains that are resistant to antibiotics and related compounds in a biological sample. Kits containing the primers and probes are also provided.
REFERENCES:
patent: WO 00/36142 (2000-06-01), None
Telenti, Mar. 1993, The Lancet, vol. 341, pp. 647 and 649.
Van Rie, Feb. 2001, J. Clin. Micro., vol. 39, pp. 637 and 638.
Rad, Jul. 2003, Emerg. Inf. Dis., vol. 9, p. 838.
Glynn, Aug. 2002, Emerg. Inf. Dis., vol. 8, p. 843.
Trautinger, Dec. 2002, EMBO J., vol. 21, p. 6944.
Altschul et al., “Gapped BLAST and PSI-BLAST: A New Generation of Protein Database Search Programs,”Nucleic Acids Research, vol. 25, pp. 3389-3402 (1997).
Bifani et al., “Identification of a W Variant Outbreak ofMycobacterium tuberculosisvia Population-Based Molecular Epidemiology,”JAMA, vol. 282, pp. 2321-2327 (1999).
Caminero et al., “Epidemiological Evidence of the Spread of aMycobacterium tuberculosisStrain of the Beijing Geneotype on Gran Canaria Island,”American Journal of Respiratory and Critical Care Medicine, vol. 164, pp. 1165-1170 (2001).
Cole et al., “Deciphering the Biology ofMycobacterium tuberculosisfrom the Complete Genome Sequence,”Nature, vol. 393, pp. 537-544 (1998).
Cunningham, Richard P., “DNA Repair: Caretakers of the Genome?,”Current Biology, pp. vol. 7, R576-R579 (1997).
Farmer et al., “Community Based Approaches to the Control of Multidrug Resistant Tuberculosis: Introducing “DOTS-plus”,”BMJ, vol. 317, pp. 671-674 (1998).
Finken et al., “Molecular Basis of Streptomycin Resistance inMycobacterium tuberculosis: Alterations of the Ribosomal Protein S12 Gene and Point Mutations Within a Functional 16S Ribosomal RNA Pseudoknot,”Molecular Microbiology, vol. 9, pp. 1239-1246 (1993).
Giraud et al., “Costs and Benefits of High Mutation Rates: Adaptive Evolution of Bacteria in the Mouse Gut,”Science, vol. 291, pp. 2606-2608 (2001).
Goguet et al., “Evaluation of Spoligotyping in a Study of the Transmission ofMycrobacterium tuberculosis,” Journal of Clinical Microbiology, vol. 35, pp. 2210-2214 (1997).
Harris et al., “Mutational, Kinetic, and NMR Studies of the Roles of Conserved Glutamate Residues and of Lysine-39 in the Mechanism of the MutT Pyrophosphohydrolase,”Biochemistry, vol 39, pp. 1655-1674 (2000).
Horst et al., “Escherichia coliMutator Genes.”Trends in Microbiology, vol. 7, pp. 29-36 (1999).
Kamerbeek et al., “Simultaneous Detection and Strain Differentiation ofMycobacterium tuberculosisfor Diagnosis and Epidemiology,”Journal of Clinical Microbiology, vol. 35, pp. 907-914 (1997).
Kremer et al., “Comparison of Methods Based on Different Molecular Epidemiological Markers for Typing ofMycobacterium tuberculosisComplex Strains: Interlaboratory Study of Discriminatory Power and Reproducibility,”Journal of Clinical Microbiology, vol. 37, pp. 2607-2618 (1999).
Kubin et al., “A Multidrug-Resistant Tuberculosis Microepidemic Caused by Genetically Closely RelatecMycrobacterium tuberculosisStrains,”Journal of Clinical Microbiology, vol. 37, pp. 2715-2716 (1999).
Kurepina et al., “Characterization of the Phylogenetic Distribution and Chromosomal Insertion Sites of Five IS6110 Elements inMycobacterium tuberculosis: Non-random Integration in the dnaA—dnaN Region,”Tubercle and Lung Disease, vol. 79, pp. 31-42 (1998).
Mizrahi et al ., “DNA Repair inMycobacterium tuberculosis. What Have we Learnt From the Genome Sequemce?,”Molecular Microbiology, vol. 29, pp. 1331-1339 (1998).
Oliver et al., “High Frequency of HypermutablePseudomonas aeruginosain Cystic Fibrosis Lung Infection,”Science, vol. 288, pp. 1251-1253 (2000).
Pfyffer et al., “Multidrug-Resistant Tuberculosis in Prison Inmates, Azerbaijan,”Emerging Infections Disease, vol. 7, pp. 855-861 (2001).
Rainey et al., “When Being Hyper Keeps you Fit,”Science, vol. 288, pp. 1186-1187 (2000).
Ritaco et al, “Nosocomial Spread of Human Immunodeficiency Virus-Related Multidrug-Resistant Tuberculosis in Buenos Aires,”The Journal of Infectious Diseases, vol. 176, pp. 637-642 (1997).
Samper et al., “The Spanish Multidrug Resistant Tuberculosis Network,”Eurosurveillance, vol. 5, pp. 43-45 (2000).
Sreevatsan et al., “Restricted Structural Gene Polymorphism in theMycrobacterium tuberculosisComplex Indicates Evolutionarily Recent Global Dissemination,”Proc. Natl. Acad Sci. USA, vol. 94, pp. 9869-9874 (1997).
Supply et al., “Automated High-Throughput Genotyping for Study of Global Epidemiology ofMycobacterium tuberculosisBased on Mycobacterial Interspersed Repetitive Units,”Journal of Clinical Microbiology, vol. 39, pp. 3563-3571 (2001).
Taddei et al., “Counteraction by MutT Protein of Transcriptional Errors Caused by Oxidative Damage,”Science, vol. 278, pp. 128-130 (1997).
Taddei et al., “Role of Mutator Alleles in Adaptive Evolution,”Nature, vol. 387, pp. 700-702 (1997).
Telenti et al., “Detection of Rifampicin-Resistance Mutations inMycobacterium tuberculosis ” The Lancet, vol. 341, pp. 647-650 (1993).
Telzak et al., “Multidrug-Resistant Tuberculosis in Patients Without HIV Infection,”The New England Journal of Medicine, vol. 333, pp. 907-911 (1995).
Tenaillon et al., “Mutators, Population Size, Adaptive Landscape and the Adaptation of Asexual Populations of Bacteria,”Genetics, vol. 152, pp. 485-493 (1999).
Van Rie et al., Analysis for a Limited Number of Gene Codons Can Predict Drug Resistance ofMycobacterium tuberculosisin a High-Incidence Community,Journal of Clinical Microbiology, vol. 39, pp. 636-641 (2001).
Van Soolingen et al., “Predominance of a Single Genotype ofMycobacterium tuberculosisin Countries of East Asia,”Journal of Clinical Microbiology, vol. 33, pp. 3234-3238 (1995).
U.S. Appl. No. 10/777,131, (WO 03/016562 A2).
Karunakaran, Ponniah et al., “Genetic Antagonism and Hypermutability inMycobacterium smegmatis,” Journal of Bacteriology, pp. 3331-3335 (2000).
Kremer, Kristin et al., “Selective Advantages of the Beijing Genotype ofM. tuberculosisin Several Georgrahic Regions,”Abstracts Oral Presentations, p. 25 (2000).
Rigouts, L. et al., “Beijing Genotype Present Among Drug-ResistantMycobacterium tuberculosisIsolates from Central and Western Asia,”Abstracts Oral Presentations, p. 26 (2000).
Office Action mailed Nov. 15, 2005, U.S. Appl. No. 10/777,131 (7 pages +4 pgs. init. PTO-1449+1 pg. PTO-892).
Bausch Sarae
Institut Pasteur
Shukla Ram R.
LandOfFree
Compositions and methods for detecting multidrug resistant... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Compositions and methods for detecting multidrug resistant..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions and methods for detecting multidrug resistant... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3808611