Compositions and methods for detecting Atopobium vaginae

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C536S024300, C435S006120, C435S091100, C435S091200

Reexamination Certificate

active

07745595

ABSTRACT:
Disclosed are oligonucleotides useful in methods for determining whether a sample containsAtopobium vaginaeor has an increased likelihood of containingAtopobium vaginae, an organism which is seen in conjunction with bacterial vaginosis or is a causative agent of bacterial vaginosis. These oligonucleotides, which have nucleotide sequences derived from a segment of the genome ofAtopobium vaginae, are useful as forward and reverse primers for a polymerase chain reaction using nucleic acids from a biological sample as a template, and as probes for detecting any resultant amplicon. Detection of an amplicon indicates the sample containsAtopobium vaginaeor has an increased likelihood of containingAtopobium vaginae.

REFERENCES:
patent: 5474796 (1995-12-01), Brennan
patent: 2001/0053519 (2001-12-01), Fodor et al.
patent: 2003/0104410 (2003-06-01), Mittmann
patent: 2005/0118625 (2005-06-01), Mounts
patent: WO0177384 (2001-10-01), None
Standford Genome Technology CenterAtopobium vaginaeGenome Project website. (.http://med.stanford.edu/sgtc/research/atopobium—vaginae.html, Jun. 14, 2006).

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