Compositions and methods for detecting and quantifying biologica

Details Compositions and methods for detecting and quantifying biologica Compositions and methods for detecting and quantifying biologica

1998-06-09

2000-05-09

Riley, Jezia

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436501, 436518, 436829, 536 221, 536 243, 536 2532, 435 71, C12Q 168, G01N 33566, C07H 1900, C07H 2100

Patent

active

060595612

ABSTRACT:
Methods and compositions for selectively detecting analytes in a homogeneous assay, a heterogeneous assay, or a mixture of the two by contacting a labeled probe:analyte complex with one or more amphiphiles. The invention is also useful for increasing the signal to noise ratio when used in conjunction with other assay systems. In preferred embodiments, the analyte and probe are nucleic acids or proteins.

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