Compositions and methods for delivery of skin cosmeceuticals

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Cosmetic – antiperspirant – dentifrice

Reexamination Certificate

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C514S844000, C514S846000, C424S078030

Reexamination Certificate

active

06984391

ABSTRACT:
New cosmetic compositions are disclosed that are effective both as moisturizers and skin sloughing agents. The compositions contain neutralized weak organic acids that when applied over time to the skin in appropriate formulations will gradually increase in acidity to pH 5.5 or less, for example about pH 4.5, without causing skin irritation while exhibiting increasing activity in skin renewal effects.

REFERENCES:
patent: 5001156 (1991-03-01), Philippe et al.
patent: 5073372 (1991-12-01), Turner et al.
patent: 5997887 (1999-12-01), Ha et al.
Berardesca, E., et al., “Differences in stratum corneum pH . . . ” Brit. J. Dermat. 139: 855-857 (19998).
Kligman, A., in Dry Skin and Moisturizers, Ed. Loden and Maibach, CRC Press, Boca Raton, 2000, p. 8.
Mauro, T. et al., “Barrier recovery is impeded at neutral . . . ” Arch Dermatol Res 290: 215-222 (1998).

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