Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1994-04-01
1998-04-14
Rories, Charles C. P.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
514 25, 514 27, 514 33, 514 35, 514 54, 514510, 514680, 514731, 514732, 435375, 435 691, 435 693, 4351721, 4351723, 4242781, 4241841, A61K 4800, C07H 1524, C12N 1564, C12N 1587
Patent
active
057391181
ABSTRACT:
Methods of introducing genetic material into cells of an individual and compositions and kits for practicing the same are disclosed. The methods comprise the steps of contacting cells of an individual with a genetic vaccine facilitator and administering to the cells, a nucleic acid molecule that is free of retroviral particles. The nucleic acid molecule comprises a nucleotide sequence that encodes a protein that comprises at least one epitope that is identical or substantially similar to an epitope of a pathogen antigen or an antigen associated with a hyperproliferative or autoimmune disease, a protein otherwise missing from the individual due to a missing, non-functional or partially functioning gene, or a protein that produce a therapeutic effect on an individual. Methods of prophylactically and therapeutically immunizing an individual against HIV are disclosed. Pharmaceutical compositions and kits for practicing methods of the present invention are disclosed.
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Carrano Richard A.
Wang Bin
Weiner David B.
Apollon, Inc.
Rories Charles C. P.
The Trustees of the University of Pennsylvania
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