Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2005-05-10
2005-05-10
Weber, Jon P. (Department: 1653)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C514S014800
Reexamination Certificate
active
06890896
ABSTRACT:
Peptide compounds and methods for upregulating expression of a gene encoding an antioxidative enzyme, such as superoxide dismutase or catalase, to counteract harmful oxidative effects of reactive oxygen species and other free radicals are described. The peptide compounds may be used to treat or prevent diseases and conditions characterized by undesirable elevation of reactive oxygen species and other free radicals, to upregulate AP-1 gene expression, and to treat pain. The peptide compounds may be used as components of pharmaceuticals and dietary supplements.
REFERENCES:
patent: 4297344 (1981-10-01), Schwinn et al.
patent: 4783441 (1988-11-01), Thurow
patent: 4812557 (1989-03-01), Yasushi et al.
patent: 5096885 (1992-03-01), Pearlman et al.
patent: 5098893 (1992-03-01), Franks et al.
patent: 5972985 (1999-10-01), Thomas et al.
patent: 6627601 (2003-09-01), Shashoua
patent: 0497341 (1992-05-01), None
patent: 2099067 (1997-12-01), None
patent: WO 9220362 (1992-11-01), None
patent: WO 9926620 (1999-06-01), None
patent: WO 9940112 (1999-08-01), None
patent: WO 0136454 (2001-05-01), None
Jornot L. and Junod, A. “Hyperoxia, unlike phorbol ester, induces glutathione peroxidase through a protein kinase C-independent mechanism.” Biochem. J. 326: 117-123 1997.*
Adams et al.,General Cellular Biochemistry, 77:221-233 (2000).
Adams et al.,J. Leukocyte Biol.,62: 865-873 (1997).
Altschul et al.,Nucl. Acids Res.25:3389-3402, 1997.
Angel et al.,Cell49:729-739, (1987).
Bederson et al.,Stroke,17:1304 (1986).
Beyer & Fridovich,Anal. Biochem.,161:559-566 (1987).
Bodanszky and Bodanszky,The Practice of Peptide Synthesis(Springer-Verlag, New York (1984).
Carpenter et al.,Pharm. Res.,14(8): 969 (1997).
Ceballos-Picot,CR Seances Soc. Biol. Fil.,187: 308-323 (1993).
Chan et al.,Adv. Neurol.,71:271-279 (1996).
Cornell-Bell et al.,Cell Calcium,12: 185-204 (1991).
Cornell-Bell et al.,Science,247: 470-473 (1990).
DiGuiseppi, J. and Fridovich, I.,Crit. Rev. Toxicol.,12:315-342 (1984).
Erdincler, D.S., et al.,Clin. Chim. Acta,265: 77-84 (1997).
Fischer et. al.,Molecular Pharm.,40:846-853, (1991).
Fridovich,Adv. Enzymol.,41:35-97 (1974).
Halliwell, B. and Gutteridge, J.M.C., eds.Free Radicals in Biology and Medicine,(Oxford: Clarendon Press, 1989).
Hanks and Wallace,Proc. Soc. Exp. Biol. Med.71:196 (1949).
Horvitz et al.,Cold Spring Harbor Symposium Quant. Biol.,111:377 (1994).
Hsu et al.,Stroke,24 (suppl. I): T-78-I-79 (1993).
Huang et al.,Chung Kuo Chung Yao Tsa Chih,16: 414-416, 447 (1991) (abstract).
Kaiser, et al.,Anal. Biochem.,34: 595-598 (1970).
Lehninger, A. L.,Biochemistry,second edition (Worth Publishers, Inc., New York, 1975), p. 72.
Li et al.,Chung Kuo Chung Yao Tsa Chih,19: 300-302 (1994) (abstract).
Li et al.,J. Cereb. Blood Flow Metab.,17:1132 (1997).
Lucchesi, B.R.,Am. J. Cardiol.,65:14I-23I (1990).
Mecocci, P. et al.,Free Radic. Biol. Med.,28: 1243-1248 (2000).
Melov, et al.,Science,289: 1567-1569 (2000).
Merrifield,J. Am. Chem. Soc.,85:2149-2154 (1963).
Minematsu et al.,Neurology,42:235 (1992).
Morganstern and Glazer,Arch. Gen. Psychiatr.,50: 723-733 (1993).
Murakami et al.,Stroke,28: 1797-1804 (1997).
Nagasawa and Kogure,Stroke,20:1037 (1989).
Niki, E.,Intern. Med.,39: 324-326 (2000).
Pulsinelli, W.A. et al.,Ann. Neurol.,11: 499-502 (1982).
Ratafia,Pharmaceutical Executive,pp. 74-80 (Apr. 1991).
Schabitz et al.,J. Cereb. Blood Flow Metabol.,17: 500-506 (1997).
Shashoua and Hesse,Life Sci.58:1347-1357 (1996).
Somani et al.,Oxidants, Antioxidants, and Free Radicals,chapter 6, pp. 125-141, Baskin, S.I. and H. Salem, eds. (Taylor & Francis, Washington, D.C., 1997).
Tabuchi et al.,J. Biol. Chem.,271: 31061-31067 (1996).
Tong and Perez-Polo,J. Neurosci. Res.,45: 1-12 (1996).
Toyokuni, S.,Pathol. Int.,49: 91-102 (1999).
Tsai et al.,Am. J. Psychiatr.,155: 1207-1253 (1998).
Walton, M. et al.,Brain Res. Rev.,29:137-168 (1999).
Wang et al.,Chung Kuo Chung Hsi I Chieh Ho Tsa Chih,12: 23-25, 5 (1992) (abstract).
Wang et al.,Chung Kuo Chung Hsi I Chieh Ho Tsa Chih,13: 349-351, 325-326 (1993) (abstract).
Yuan et al.,Cell75: 641 (1993).
Zea Longa et al.,Stroke,20: 84 (1989).
EP Supplemental Search Report Dec. 2, 2004.
EP Supplemental Search Report Apr. 6, 2003.
PCT Search Report Apr. 7, 2001.
CereMedix, Inc.
Desai Anand
Weber Jon P.
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