Compositions and methods for controlling pest insects

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514262, 514263, 514264, 514275, 424 84, A01N 4354, A01N 4390

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active

056209827

ABSTRACT:
Compositions of a purine, a xanthine oxidase inhibitor and/or a dihydrofolate reductase inhibitor, and methods of using same, for controlling the growth of pest insects which salvage, store, or excrete their nitrogenous wastes via the purine metabolic pathway.

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patent: 4902690 (1990-02-01), Nathanson
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Engebretson & Mullins, "Effects of a Purine Inhibitor, Allopurinol, on Urate Metabolism in the German Cockroach, Blattella Germanica L. (Dictyoptera: Blattellidae)", Comp. Biochem. Physiol. 83B(1):93-97 (1986).
Suiter et al., "Dietary Effects of Allopurinol and Sulfinpyrazone on Development, Survival, and Reproduction of German Cockroaches (Dictyoptera: Blattellidae)", J. Econ. Entomol. 85(1):117-122 (1992).
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Wigglesworth, "Histochemical Studies of Uric Acid in Some Insects. I. Storage in the Fat Body of Periplaneta Americana and the Action of the Symbiotic Bacteria", Tissue and Cell 19(1):83-91. (1987).
Cochran, "Comparative Analysis of Excreta from Twenty Cockroach Species", Comp. Biochem. Physiol. 46A:409-419 (1973).
Mullins & Cochran, "Nitrogen Excretion in Cockroaches: Uric Acid is Not a Major Product", Science 177:699-701 (1972).
Massey et al., "On the Mechanism of Inactivation of Xanthine Oxidase by Allopurinol and Other Pyrazolo[3,4-d]pyrimidines", J. Biol. Chem. 245(11):2837-2844 (1970).
Slansky, "Xanthine Toxicity to Caterpillars Synergized by Allopurinol, a Xanthine Dehyrdogenase/Oxidase Inhibitor", J. Chem. Ecol. 19(11):2635-2650 (1993).

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