Compositions and methods for cell transformation

Details Compositions and methods for cell transformation Compositions and methods for cell transformation

1995-04-20

1998-07-14

Kight, John

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514169, 514170, 514178, 514182, 536 5, 930 10, A61K 31705, A61K 3156, C07J 100

Patent

active

057804443

ABSTRACT:
The present invention relates to methods and compositions for the transformation of cells. In particular, compositions and methods are disclosed which include combinations of the nucleic acid of interest and polyhydroxylated or polyglycosylated steroid molecules. Most preferably, exogenous or endogenous nucleic acid is contacted with the cell in the presence of a bile acid (e.g., cholic acid) derivatized with an amine-containing side chain.

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